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Ligase 1 is a predictor of platinum resistance and its blockade is synthetically lethal in XRCC1 deficient epithelial ovarian cancers.
Ali, Reem; Alabdullah, Muslim; Algethami, Mashael; Alblihy, Adel; Miligy, Islam; Shoqafi, Ahmed; Mesquita, Katia A; Abdel-Fatah, Tarek; Chan, Stephen Yt; Chiang, Pei Wen; Mongan, Nigel P; Rakha, Emad A; Tomkinson, Alan E; Madhusudan, Srinivasan.
Afiliação
  • Ali R; Nottingham Biodiscovery Institute, School of Medicine, University of Nottingham, University Park, Nottingham NG7 3RD, UK.
  • Alabdullah M; Nottingham Biodiscovery Institute, School of Medicine, University of Nottingham, University Park, Nottingham NG7 3RD, UK.
  • Algethami M; Department of Pathology, Division of Cancer and Stem Cells, School of Medicine, University of Nottingham, Nottingham NG51PB, UK.
  • Alblihy A; Nottingham Biodiscovery Institute, School of Medicine, University of Nottingham, University Park, Nottingham NG7 3RD, UK.
  • Miligy I; Nottingham Biodiscovery Institute, School of Medicine, University of Nottingham, University Park, Nottingham NG7 3RD, UK.
  • Shoqafi A; Medical Center, King Fahad Security College (KFSC), Riyadh 11461, Saudi Arabia.
  • Mesquita KA; Department of Pathology, Division of Cancer and Stem Cells, School of Medicine, University of Nottingham, Nottingham NG51PB, UK.
  • Abdel-Fatah T; Nottingham Biodiscovery Institute, School of Medicine, University of Nottingham, University Park, Nottingham NG7 3RD, UK.
  • Chan SY; Nottingham Biodiscovery Institute, School of Medicine, University of Nottingham, University Park, Nottingham NG7 3RD, UK.
  • Chiang PW; Department of Oncology, Nottingham University Hospitals, City Hospital Campus, Nottingham NG5 1PB, UK.
  • Mongan NP; Department of Oncology, Nottingham University Hospitals, City Hospital Campus, Nottingham NG5 1PB, UK.
  • Rakha EA; Department of Obstetrics & Gynaecology, Queens Medical Centre, Nottingham University Hospitals, Nottingham NG7 2UH, UK.
  • Tomkinson AE; Faculty of Medicine and Health Sciences, Centre for Cancer Sciences, University of Nottingham, Sutton Bonington Campus, Sutton Bonington, Leicestershire LE12 5RD, UK.
  • Madhusudan S; Department of Pharmacology, Weill Cornell Medicine, New York, NY, 10065, USA.
Theranostics ; 11(17): 8350-8361, 2021.
Article em En | MEDLINE | ID: mdl-34373746
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: DNA Ligase Dependente de ATP / Proteína 1 Complementadora Cruzada de Reparo de Raio-X / Carcinoma Epitelial do Ovário Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Adult / Female / Humans / Middle aged Idioma: En Revista: Theranostics Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Reino Unido
Texto completo
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Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: DNA Ligase Dependente de ATP / Proteína 1 Complementadora Cruzada de Reparo de Raio-X / Carcinoma Epitelial do Ovário Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Adult / Female / Humans / Middle aged Idioma: En Revista: Theranostics Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Reino Unido