Use of a neuron-glia genome-scale metabolic reconstruction to model the metabolic consequences of the Arylsulphatase a deficiency through a systems biology approach.

Echeverri-Peña, Olga Y; Salazar-Barreto, Diego A; Rodríguez-Lopez, Alexander; González, Janneth; Alméciga-Díaz, Carlos J; Verano-Guevara, Cristian H; Barrera, Luis A

Echeverri-Peña, Olga Y; Salazar-Barreto, Diego A; Rodríguez-Lopez, Alexander; González, Janneth; Alméciga-Díaz, Carlos J; Verano-Guevara, Cristian H; Barrera, Luis A.

Afiliação

Echeverri-Peña OY; Institute for the Study of Inborn Errors of Metabolism, Faculty of Science, Pontificia Universidad Javeriana, Bogotá D.C., Colombia.
Salazar-Barreto DA; Centro para la Optimización y Probabilidad Aplicada (COPA), Department of Industrial Engineering, Faculty of Engineering, Universidad de los Andes, Bogotá D.C., Colombia.
Rodríguez-Lopez A; Grupo de Bioquímica Computacional, Estructural y Bioinformática, Department of Nutrition and Biochemistry, Faculty of Science, Pontificia Universidad Javeriana, Bogotá, Colombia.
González J; Institute for the Study of Inborn Errors of Metabolism, Faculty of Science, Pontificia Universidad Javeriana, Bogotá D.C., Colombia.
Alméciga-Díaz CJ; Licenciatura en Química, Universidad Distrital Francisco Jose de Caldas, Bogota D.C., Colombia.
Verano-Guevara CH; Molecular Biology and Immunology Department, Fundación Instituto de Inmunología de Colombia (FIDIC), Bogotá D.C., Colombia.
Barrera LA; Grupo de Bioquímica Computacional, Estructural y Bioinformática, Department of Nutrition and Biochemistry, Faculty of Science, Pontificia Universidad Javeriana, Bogotá, Colombia.

Heliyon ; 7(7): e07671, 2021 Jul.

Article em En | MEDLINE | ID: mdl-34381909

Palavras-chave

Arylsulphatase A; Metachromatic leukodystrophy; Myelin sheath; System biology

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Idioma: En Revista: Heliyon Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Colômbia

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