Incidence of interruptive penicillin allergy alerts in patients with previously documented beta-lactam exposure: Potential for leveraging the electronic health record to identify erroneous allergies.
Infect Control Hosp Epidemiol
; 43(9): 1108-1111, 2022 09.
Article
em En
| MEDLINE
| ID: mdl-34387180
ABSTRACT
BACKGROUND:
Approximately 10% of patients report allergies to penicillin, yet >90% of these allergies are not clinically significant. Patients reporting penicillin allergies are often treated with second-line, non-ß-lactam antibiotics that are typically broader spectrum and more toxic. Orders for ß-lactam antibiotics for these patients trigger interruptive alerts, even when there is electronic health record (EHR) data indicating prior ß-lactam exposure.OBJECTIVE:
To describe the rate that interruptive penicillin allergy alerts display for patients who have previously had a ß-lactam exposure.DESIGN:
Retrospective EHR review from January 2013 through June 2018.SETTING:
A nonprofit health system including 1 large tertiary-care medical center, a smaller associated hospital, 2 emergency departments, and Ë250 outpatient clinics.PARTICIPANTS:
All patients with EHR-documented of penicillin allergies.METHODS:
We examined interruptive penicillin allergy alerts and identified the number and percentage of alerts that display for patients with a prior administration of a penicillin class or other ß-lactam antibiotic.RESULTS:
Of 115,081 allergy alerts that displayed during the study period, 8% were displayed for patients who had an inpatient administration of a penicillin antibiotic after the allergy was noted, and 49% were displayed for patients with a prior inpatient administration of any ß-lactam.CONCLUSIONS:
Many interruptive penicillin allergy alerts display for patients who would likely tolerate a penicillin, and half of all alerts display for patients who would likely tolerate another ß-lactam.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Beta-Lactamas
/
Hipersensibilidade a Drogas
Tipo de estudo:
Diagnostic_studies
/
Incidence_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Humans
Idioma:
En
Revista:
Infect Control Hosp Epidemiol
Assunto da revista:
DOENCAS TRANSMISSIVEIS
/
ENFERMAGEM
/
EPIDEMIOLOGIA
/
HOSPITAIS
Ano de publicação:
2022
Tipo de documento:
Article
País de afiliação:
Estados Unidos