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Novel, selective acrylamide linked quinazolines for the treatment of double mutant EGFR-L858R/T790M Non-Small-Cell lung cancer (NSCLC).
Pawara, Rahul; Ahmad, Iqrar; Nayak, Deepika; Wagh, Shivani; Wadkar, Avinash; Ansari, Azim; Belamkar, Sateesh; Surana, Sanjay; Nath Kundu, Chanakya; Patil, Chandragauda; Patel, Harun.
Afiliação
  • Pawara R; Division of Computer-Aided Drug Design, Dept. of Pharmaceutical Chemistry, R. C. Patel Institute of Pharmaceutical Education and Research, Shirpur, District, Dhule 425 405, Maharashtra, India.
  • Ahmad I; Division of Computer-Aided Drug Design, Dept. of Pharmaceutical Chemistry, R. C. Patel Institute of Pharmaceutical Education and Research, Shirpur, District, Dhule 425 405, Maharashtra, India.
  • Nayak D; Cancer Biology Division, KIIT School of Biotechnology, Kalinga Institute of Industrial Technology, Campus-11, Patia, Bhubaneswar 751024, Odisha, India.
  • Wagh S; Division of Computer-Aided Drug Design, Dept. of Pharmaceutical Chemistry, R. C. Patel Institute of Pharmaceutical Education and Research, Shirpur, District, Dhule 425 405, Maharashtra, India.
  • Wadkar A; Division of Computer-Aided Drug Design, Dept. of Pharmaceutical Chemistry, R. C. Patel Institute of Pharmaceutical Education and Research, Shirpur, District, Dhule 425 405, Maharashtra, India.
  • Ansari A; Department of Pharmaceutical Chemistry, Shri Vile Parle Kelavani Mandal's Institute of Pharmacy, Dhule 424001, Maharashtra, India.
  • Belamkar S; Shobhaben Pratapbhai Patel School of Pharmacy and Technology Management, SVKMs NMIMS V. L. Mehta Road Vile Parle (W) Mumbai, 400056, Maharashtra, India.
  • Surana S; Division of Computer-Aided Drug Design, Dept. of Pharmaceutical Chemistry, R. C. Patel Institute of Pharmaceutical Education and Research, Shirpur, District, Dhule 425 405, Maharashtra, India.
  • Nath Kundu C; Cancer Biology Division, KIIT School of Biotechnology, Kalinga Institute of Industrial Technology, Campus-11, Patia, Bhubaneswar 751024, Odisha, India.
  • Patil C; Department of Pharmacology, Delhi Pharmaceutical Sciences and Research University, New Delhi 110017, India.
  • Patel H; Division of Computer-Aided Drug Design, Dept. of Pharmaceutical Chemistry, R. C. Patel Institute of Pharmaceutical Education and Research, Shirpur, District, Dhule 425 405, Maharashtra, India. Electronic address: hpatel_38@yahoo.com.
Bioorg Chem ; 115: 105234, 2021 10.
Article em En | MEDLINE | ID: mdl-34399322
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Quinazolinas / Carcinoma Pulmonar de Células não Pequenas / Acrilamida / Inibidores de Proteínas Quinases / Neoplasias Pulmonares / Antineoplásicos Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Bioorg Chem Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Índia
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Quinazolinas / Carcinoma Pulmonar de Células não Pequenas / Acrilamida / Inibidores de Proteínas Quinases / Neoplasias Pulmonares / Antineoplásicos Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Bioorg Chem Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Índia