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Preclinical evaluation of (S)-[18F]GE387, a novel 18-kDa translocator protein (TSPO) PET radioligand with low binding sensitivity to human polymorphism rs6971.
Ramakrishnan, Nisha K; Hird, Matthew; Thompson, Stephen; Williamson, David J; Qiao, Luxi; Owen, David R; Brooks, Allen F; Scott, Peter J H; Bacallado, Sergio; O'Brien, John T; Aigbirhio, Franklin I.
Afiliação
  • Ramakrishnan NK; Molecular Imaging Chemistry Laboratory, Wolfson Brain Imaging Centre, Department of Clinical Neurosciences, University of Cambridge, Biomedical Campus, Cambridge, CB2 0SZ, UK. nk473@cam.ac.uk.
  • Hird M; Molecular Imaging Chemistry Laboratory, Wolfson Brain Imaging Centre, Department of Clinical Neurosciences, University of Cambridge, Biomedical Campus, Cambridge, CB2 0SZ, UK.
  • Thompson S; Molecular Imaging Chemistry Laboratory, Wolfson Brain Imaging Centre, Department of Clinical Neurosciences, University of Cambridge, Biomedical Campus, Cambridge, CB2 0SZ, UK.
  • Williamson DJ; Molecular Imaging Chemistry Laboratory, Wolfson Brain Imaging Centre, Department of Clinical Neurosciences, University of Cambridge, Biomedical Campus, Cambridge, CB2 0SZ, UK.
  • Qiao L; Molecular Imaging Chemistry Laboratory, Wolfson Brain Imaging Centre, Department of Clinical Neurosciences, University of Cambridge, Biomedical Campus, Cambridge, CB2 0SZ, UK.
  • Owen DR; Department of Brain Sciences, Imperial College London, Hammersmith Hospital, London, UK.
  • Brooks AF; Division of Nuclear Medicine, Department of Radiology, University of Michigan Medical School, 1301 Catherine Street, Ann Arbor, MI, 48109, USA.
  • Scott PJH; Division of Nuclear Medicine, Department of Radiology, University of Michigan Medical School, 1301 Catherine Street, Ann Arbor, MI, 48109, USA.
  • Bacallado S; Statistical Laboratory, Centre for the Mathematical Sciences, University of Cambridge, Wilberforce Rd., Cambridge, CB3 0WB, UK.
  • O'Brien JT; Department of Psychiatry, School of Clinical Medicine, University of Cambridge, Cambridge Biomedical Campus, Cambridge, UK.
  • Aigbirhio FI; Molecular Imaging Chemistry Laboratory, Wolfson Brain Imaging Centre, Department of Clinical Neurosciences, University of Cambridge, Biomedical Campus, Cambridge, CB2 0SZ, UK.
Eur J Nucl Med Mol Imaging ; 49(1): 125-136, 2021 12.
Article em En | MEDLINE | ID: mdl-34405276
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Receptores de GABA / Compostos Radiofarmacêuticos Tipo de estudo: Diagnostic_studies / Prognostic_studies Limite: Animals / Female / Humans / Male Idioma: En Revista: Eur J Nucl Med Mol Imaging Assunto da revista: MEDICINA NUCLEAR Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Reino Unido
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Receptores de GABA / Compostos Radiofarmacêuticos Tipo de estudo: Diagnostic_studies / Prognostic_studies Limite: Animals / Female / Humans / Male Idioma: En Revista: Eur J Nucl Med Mol Imaging Assunto da revista: MEDICINA NUCLEAR Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Reino Unido