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A novel angular dependency model for MatriXX response and its application to true composite dose verification for IMRT plans.
Zhou, Yin; Sang, Jiugao; Chen, Haibo; Zhu, Meng; Wang, He; Zhai, Shuwei; Lu, Lina; Liu, Hui; Zhu, Zhengfei; Hui, Zhouguang; Dai, Jianrong; Huan, Jian.
Afiliação
  • Zhou Y; Evidance Medical Technologies Inc., Suzhou, China.
  • Sang J; Department of Radiation Oncology, Rudong County People's Hospital, Rudong, China.
  • Chen H; Department of Radiation Oncology, The Affiliated Suzhou Science and Technology Town Hospital of Nanjing Medical University, Suzhou, China.
  • Zhu M; Evidance Medical Technologies Inc., Suzhou, China.
  • Wang H; Homology Medical Technologies Inc., Ningbo, China.
  • Zhai S; Department of Radiation Oncology, The Affiliated Suzhou Science and Technology Town Hospital of Nanjing Medical University, Suzhou, China.
  • Lu L; Department of Radiation Oncology, The Affiliated Suzhou Science and Technology Town Hospital of Nanjing Medical University, Suzhou, China.
  • Liu H; Department of Radiation Oncology, State Key Laboratory of Oncology in South China, Sun Yat-sen University Cancer Center, Guangzhou, China.
  • Zhu Z; Department of Radiation Oncology, Fudan University Shanghai Cancer Center, Shanghai, China.
  • Hui Z; Department of Radiation Oncology, National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
  • Dai J; Department of Radiation Oncology, National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
  • Huan J; Department of Radiation Oncology, The Affiliated Suzhou Science and Technology Town Hospital of Nanjing Medical University, Suzhou, China.
J Appl Clin Med Phys ; 22(10): 120-135, 2021 Oct.
Article em En | MEDLINE | ID: mdl-34453876
ABSTRACT

PURPOSE:

This paper proposes a model for the angular dependency of MatriXX response and investigates whether MatriXX, with the angular-model-based approach can be applied to true composite dose verification for IMRT plans.

METHOD:

This model attributes the angular dependence of MatriXX response to dynamical translation of its effective measurement plane (EMP) due to the change of beam angle. Considering this mechanism, true composite dose verifications for IMRT plans specified in AAPM TG 119 report using both MatriXX and Gafchromic EBT3 films were undertook and compared to validate the applicability of MatriXX for patient specific QA of composite beam IMRT plans. Dose verifications using MatriXX with and without angular-model-based approach were performed.

RESULTS:

MatriXX with angular-model-based approach achieved gamma passing rates with 3%/3 mm and 3%/2 mm criteria better than 98.3% and 98.1% respectively for true composite dose verification of plans in AAPM TG 119 report. The 3%/3 mm and 3%/2 mm gamma passing rates using MatriXX without angular-model-based approach ranged from 85.8% to 98.2% and from 81.3% to 96.5%, respectively. The p-values from the single sided paired t-test indicated no statistical difference between the passing rates from MatriXX with angular-model-based approach and from films, and significant difference between the passing rates from uncorrected MatriXX and from films.

CONCLUSION:

The proposed model for angular dependent MatriXX response is necessary and effective. Dose verification using MatriXX with angular-model-based approach is acceptable for true composite beam IMRT plans with required accuracy to simplify patient specific QA.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Radioterapia de Intensidade Modulada Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: J Appl Clin Med Phys Assunto da revista: BIOFISICA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: China

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Radioterapia de Intensidade Modulada Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: J Appl Clin Med Phys Assunto da revista: BIOFISICA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: China