Surgical protocol for permanent ligation of the left anterior descending coronary artery in mice to generate a model of myocardial infarction.
STAR Protoc
; 2(3): 100775, 2021 09 17.
Article
em En
| MEDLINE
| ID: mdl-34485941
ABSTRACT
Myocardial infarction (MI) is one of the most common causes of death worldwide. Animal models for MI are useful for studying the pathophysiology and developing therapies. Here, we describe a surgical protocol for permanent ligation of the left anterior descending coronary artery in mice, which mimics human acute coronary syndrome. This protocol includes descriptive step-by-step surgical procedures and high-quality surgical videos, which are useful for performing stable and highly reproducible operations. For complete details on the use and execution of this protocol, please refer to Maruyama et al. (2021).
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Procedimentos Cirúrgicos Cardiovasculares
/
Vasos Coronários
/
Ligadura
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Modelos Cardiovasculares
/
Infarto do Miocárdio
Tipo de estudo:
Guideline
Limite:
Animals
Idioma:
En
Revista:
STAR Protoc
Ano de publicação:
2021
Tipo de documento:
Article
País de afiliação:
Japão