Leveraging genetic data to investigate the effects of interleukin-6 receptor signalling on levels of 40 circulating cytokines.

Rahman, Rezbieara P; McEwan, Lauren; Ryan, David K; Gill, Dipender

Rahman, Rezbieara P; McEwan, Lauren; Ryan, David K; Gill, Dipender.

Afiliação

Rahman RP; Clinical Pharmacology and Therapeutics Section, Institute for Infection and Immunity, St George's, University of London, London, UK.
McEwan L; Clinical Pharmacology and Therapeutics Section, Institute for Infection and Immunity, St George's, University of London, London, UK.
Ryan DK; Clinical Pharmacology and Therapeutics Section, Institute for Infection and Immunity, St George's, University of London, London, UK.
Gill D; Clinical Pharmacology Group, Pharmacy and Medicines Directorate, St George's University Hospitals NHS Foundation Trust, London, UK.

Br J Clin Pharmacol ; 88(3): 1373-1378, 2022 03.

Article em En | MEDLINE | ID: mdl-34506050

Assuntos

Citocinas; Estudo de Associação Genômica Ampla; Citocinas/genética; Humanos; Interleucina-6/metabolismo; Análise da Randomização Mendeliana/métodos; Receptores de Interleucina-6/genética

Palavras-chave

Mendelian randomization; cytokines; inflammation; interleukin 6; interleukin 6 receptor

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Citocinas / Estudo de Associação Genômica Ampla Tipo de estudo: Clinical_trials / Prognostic_studies Limite: Humans Idioma: En Revista: Br J Clin Pharmacol Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Reino Unido

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