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Fc-engineered antibody therapeutics with improved anti-SARS-CoV-2 efficacy.
Yamin, Rachel; Jones, Andrew T; Hoffmann, Hans-Heinrich; Schäfer, Alexandra; Kao, Kevin S; Francis, Rebecca L; Sheahan, Timothy P; Baric, Ralph S; Rice, Charles M; Ravetch, Jeffrey V; Bournazos, Stylianos.
Afiliação
  • Yamin R; Laboratory of Molecular Genetics and Immunology, The Rockefeller University, New York, NY, USA.
  • Jones AT; Laboratory of Molecular Genetics and Immunology, The Rockefeller University, New York, NY, USA.
  • Hoffmann HH; Laboratory of Virology and Infectious Disease, The Rockefeller University, New York, NY, USA.
  • Schäfer A; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
  • Kao KS; Laboratory of Molecular Genetics and Immunology, The Rockefeller University, New York, NY, USA.
  • Francis RL; Laboratory of Molecular Genetics and Immunology, The Rockefeller University, New York, NY, USA.
  • Sheahan TP; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
  • Baric RS; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
  • Rice CM; Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
  • Ravetch JV; Laboratory of Virology and Infectious Disease, The Rockefeller University, New York, NY, USA.
  • Bournazos S; Laboratory of Molecular Genetics and Immunology, The Rockefeller University, New York, NY, USA. ravetch@rockefeller.edu.
Nature ; 599(7885): 465-470, 2021 11.
Article em En | MEDLINE | ID: mdl-34547765

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fragmentos Fc das Imunoglobulinas / SARS-CoV-2 / COVID-19 / Tratamento Farmacológico da COVID-19 / Anticorpos Monoclonais Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans / Male Idioma: En Revista: Nature Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fragmentos Fc das Imunoglobulinas / SARS-CoV-2 / COVID-19 / Tratamento Farmacológico da COVID-19 / Anticorpos Monoclonais Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans / Male Idioma: En Revista: Nature Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos