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Selective Induction of Cell Death in Human M1 Macrophages by Smac Mimetics Is Mediated by cIAP-2 and RIPK-1/3 through the Activation of mTORC.
Ali, Hamza; Dong, Simon Xin Min; Gajanayaka, Niranjala; Cassol, Edana; Angel, Jonathan B; Kumar, Ashok.
Afiliação
  • Ali H; Department of Biochemistry, Microbiology, and Immunology, University of Ottawa, Ontario, Canada; akumar@uottawa.ca heid@taibahu.edu.sa.
  • Dong SXM; Apoptosis Research Centre, Children's Hospital of Eastern Ontario Research Institute, University of Ottawa, Ottawa, Ontario, Canada.
  • Gajanayaka N; Faculty of Applied Medical Sciences, Taibah University, Medina, Kingdom of Saudi Arabia.
  • Cassol E; Apoptosis Research Centre, Children's Hospital of Eastern Ontario Research Institute, University of Ottawa, Ottawa, Ontario, Canada.
  • Angel JB; Apoptosis Research Centre, Children's Hospital of Eastern Ontario Research Institute, University of Ottawa, Ottawa, Ontario, Canada.
  • Kumar A; Department of Health Sciences, Carleton University, Ottawa, Ontario, Canada.
J Immunol ; 207(9): 2359-2373, 2021 11 01.
Article em En | MEDLINE | ID: mdl-34561230
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Artrite Reumatoide / Doenças Inflamatórias Intestinais / Biomimética / Alvo Mecanístico do Complexo 1 de Rapamicina / Alvo Mecanístico do Complexo 2 de Rapamicina / Macrófagos Limite: Humans Idioma: En Revista: J Immunol Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Artrite Reumatoide / Doenças Inflamatórias Intestinais / Biomimética / Alvo Mecanístico do Complexo 1 de Rapamicina / Alvo Mecanístico do Complexo 2 de Rapamicina / Macrófagos Limite: Humans Idioma: En Revista: J Immunol Ano de publicação: 2021 Tipo de documento: Article