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Panache: a web browser-based viewer for linearized pangenomes.
Durant, Éloi; Sabot, François; Conte, Matthieu; Rouard, Mathieu.
Afiliação
  • Durant É; DIADE, Univ Montpellier, CIRAD, IRD, Montpellier 34830, France.
  • Sabot F; Syngenta Seeds SAS, Saint-Sauveur 31790, France.
  • Conte M; Bioversity International, Parc Scientifique Agropolis II, Montpellier 34397, France.
  • Rouard M; French Institute of Bioinformatics (IFB)-South Green Bioinformatics Platform, Bioversity, CIRAD, INRAE, IRD, Montpellier 34398, France.
Bioinformatics ; 37(23): 4556-4558, 2021 12 07.
Article em En | MEDLINE | ID: mdl-34601567
ABSTRACT
MOTIVATION Pangenomics evolved since its first applications on bacteria, extending from the study of genes for a given population to the study of all of its sequences available. While multiple methods are being developed to construct pangenomes in eukaryotic species there is still a gap for efficient and user-friendly visualization tools. Emerging graph representations come with their own challenges, and linearity remains a suitable option for user-friendliness.

RESULTS:

We introduce Panache, a tool for the visualization and exploration of linear representations of gene-based and sequence-based pangenomes. It uses a layout similar to genome browsers to display presence absence variations and additional tracks along a linear axis with a pangenomics perspective. AVAILABILITY AND IMPLEMENTATION Panache is available at github.com/SouthGreenPlatform/panache under the MIT License.
Assuntos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Software / Genoma Idioma: En Revista: Bioinformatics Assunto da revista: INFORMATICA MEDICA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: França

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Software / Genoma Idioma: En Revista: Bioinformatics Assunto da revista: INFORMATICA MEDICA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: França