Increased myofilament calcium sensitivity is associated with decreased cardiac troponin I phosphorylation in the diabetic rat heart.

Greenman, Angela C; Diffee, Gary M; Power, Amelia S; Wilkins, Gerard T; Gold, Olivia M S; Erickson, Jeffrey R; Baldi, James C

Greenman, Angela C; Diffee, Gary M; Power, Amelia S; Wilkins, Gerard T; Gold, Olivia M S; Erickson, Jeffrey R; Baldi, James C.

Afiliação

Greenman AC; Department of Medicine, Otago Medical School, University of Otago, Dunedin, New Zealand.
Diffee GM; Department of Physiology, School of Biomedical Sciences, University of Otago, Dunedin, New Zealand.
Power AS; HeartOtago, University of Otago, Dunedin, New Zealand.
Wilkins GT; Department of Kinesiology, University of Wisconsin-Madison, Madison, WI, USA.
Gold OMS; Department of Physiology, School of Biomedical Sciences, University of Otago, Dunedin, New Zealand.
Erickson JR; HeartOtago, University of Otago, Dunedin, New Zealand.
Baldi JC; Department of Medicine, Otago Medical School, University of Otago, Dunedin, New Zealand.

Exp Physiol ; 106(11): 2235-2247, 2021 11.

Article em En | MEDLINE | ID: mdl-34605091

Assuntos

Diabetes Mellitus; Miofibrilas; Animais; Cálcio/metabolismo; Diabetes Mellitus/metabolismo; Miocárdio/metabolismo; Miócitos Cardíacos/metabolismo; Miofibrilas/metabolismo; Fosforilação/fisiologia; Ratos; Ratos Zucker; Troponina I/metabolismo

Palavras-chave

O-GlcNAcylation; diabetes; heart failure; myofilament function; phosphorylation

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Diabetes Mellitus / Miofibrilas Tipo de estudo: Diagnostic_studies / Risk_factors_studies Limite: Animals Idioma: En Revista: Exp Physiol Assunto da revista: FISIOLOGIA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Nova Zelândia

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