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The structure of nontypeable Haemophilus influenzae SapA in a closed conformation reveals a constricted ligand-binding cavity and a novel RNA binding motif.
Lukacik, Petra; Owen, C David; Harris, Gemma; Bolla, Jani Reddy; Picaud, Sarah; Alibay, Irfan; Nettleship, Joanne E; Bird, Louise E; Owens, Raymond J; Biggin, Philip C; Filippakopoulos, Panagis; Robinson, Carol V; Walsh, Martin A.
Afiliação
  • Lukacik P; Diamond Light Source, Harwell Science & Innovation Campus, Didcot, Oxfordshire, United Kingdom.
  • Owen CD; Research Complex at Harwell, Harwell Science and Innovation Campus, Didcot, Oxfordshire, United Kingdom.
  • Harris G; Diamond Light Source, Harwell Science & Innovation Campus, Didcot, Oxfordshire, United Kingdom.
  • Bolla JR; Research Complex at Harwell, Harwell Science and Innovation Campus, Didcot, Oxfordshire, United Kingdom.
  • Picaud S; Research Complex at Harwell, Harwell Science and Innovation Campus, Didcot, Oxfordshire, United Kingdom.
  • Alibay I; Department of Chemistry, University of Oxford, Oxford, United Kingdom.
  • Nettleship JE; Structural Genomics Consortium, University of Oxford, Oxford, United Kingdom.
  • Bird LE; Department of Biochemistry, University of Oxford, Oxford, United Kingdom.
  • Owens RJ; Research Complex at Harwell, Harwell Science and Innovation Campus, Didcot, Oxfordshire, United Kingdom.
  • Biggin PC; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom.
  • Filippakopoulos P; Research Complex at Harwell, Harwell Science and Innovation Campus, Didcot, Oxfordshire, United Kingdom.
  • Robinson CV; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom.
  • Walsh MA; Research Complex at Harwell, Harwell Science and Innovation Campus, Didcot, Oxfordshire, United Kingdom.
PLoS One ; 16(10): e0256070, 2021.
Article em En | MEDLINE | ID: mdl-34653190
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: RNA de Cadeia Dupla / Proteínas de Transporte / Haemophilus influenzae / Transportadores de Cassetes de Ligação de ATP / Heme Tipo de estudo: Prognostic_studies Idioma: En Revista: PLoS One Assunto da revista: CIENCIA / MEDICINA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Reino Unido
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: RNA de Cadeia Dupla / Proteínas de Transporte / Haemophilus influenzae / Transportadores de Cassetes de Ligação de ATP / Heme Tipo de estudo: Prognostic_studies Idioma: En Revista: PLoS One Assunto da revista: CIENCIA / MEDICINA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Reino Unido