DNA Damage Repair Deficiency in Pancreatic Ductal Adenocarcinoma: Preclinical Models and Clinical Perspectives.

Stoof, Jojanneke; Harrold, Emily; Mariottino, Sarah; Lowery, Maeve A; Walsh, Naomi

Stoof, Jojanneke; Harrold, Emily; Mariottino, Sarah; Lowery, Maeve A; Walsh, Naomi.

Afiliação

Stoof J; Trinity St. James Cancer Institute, Trinity College Dublin, Dublin, Ireland.
Harrold E; Trinity College Dublin, Dublin, Ireland.
Mariottino S; Mater Private Hospital, Dublin, Ireland.
Lowery MA; Trinity St. James Cancer Institute, Trinity College Dublin, Dublin, Ireland.
Walsh N; Trinity St. James Cancer Institute, Trinity College Dublin, Dublin, Ireland.

Front Cell Dev Biol ; 9: 749490, 2021.

Article em En | MEDLINE | ID: mdl-34712667

Palavras-chave

DNA damage response (DDR); cell line; genetically engineered mouse model (GEMM); organoid; pancreatic duct adenocarcinoma (PDAC); preclinical model; targeted therapy; xenograft

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Idioma: En Revista: Front Cell Dev Biol Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Irlanda

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