Genome Editing in iPSC-Based Neural Systems: From Disease Models to Future Therapeutic Strategies.

McTague, Amy; Rossignoli, Giada; Ferrini, Arianna; Barral, Serena; Kurian, Manju A

McTague, Amy; Rossignoli, Giada; Ferrini, Arianna; Barral, Serena; Kurian, Manju A.

Afiliação

McTague A; Developmental Neurosciences, Great Ormond Street Institute of Child Health, University College London, London, United Kingdom.
Rossignoli G; Department of Neurology, Great Ormond Street Hospital, London, United Kingdom.
Ferrini A; Developmental Neurosciences, Great Ormond Street Institute of Child Health, University College London, London, United Kingdom.
Barral S; Developmental Neurosciences, Great Ormond Street Institute of Child Health, University College London, London, United Kingdom.
Kurian MA; Developmental Neurosciences, Great Ormond Street Institute of Child Health, University College London, London, United Kingdom.

Front Genome Ed ; 3: 630600, 2021.

Article em En | MEDLINE | ID: mdl-34713254

Palavras-chave

CRISPR; CRISPRa; CRISPRi; disease modeling; gene editing; induced pluripotent stem cells; neurological disorders; precision treatment

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Front Genome Ed Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Reino Unido

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