Fish-specific TLR18 in Nile tilapia (Oreochromis niloticus) recruits MyD88 and TRIF to induce expression of effectors in NF-&#954;B and IFN pathways in melanomacrophages.

Trung, Nguyen Bao; Nan, Fan-Hua; Lee, Meng-Chou; Loh, Jiun-Yan; Gong, Hong-Yi; Lu, Ming-Wei; Hang, Ho Thi; Lin, Yu-Lin; Lee, Po-Tsang

Fish-specific TLR18 in Nile tilapia (Oreochromis niloticus) recruits MyD88 and TRIF to induce expression of effectors in NF-κB and IFN pathways in melanomacrophages.

Trung, Nguyen Bao; Nan, Fan-Hua; Lee, Meng-Chou; Loh, Jiun-Yan; Gong, Hong-Yi; Lu, Ming-Wei; Hang, Ho Thi; Lin, Yu-Lin; Lee, Po-Tsang.

Afiliação

Trung NB; Department of Aquaculture, National Taiwan Ocean University, Keelung, Taiwan, ROC; College of Aquaculture and Fisheries, Can Tho University, Viet Nam.
Nan FH; Department of Aquaculture, National Taiwan Ocean University, Keelung, Taiwan, ROC; Center of Excellence for Ocean Engineering, National Taiwan Ocean University, 11, Keelung City, 20224, Taiwan.
Lee MC; Department of Aquaculture, National Taiwan Ocean University, Keelung, Taiwan, ROC; Center of Excellence for Ocean Engineering, National Taiwan Ocean University, 11, Keelung City, 20224, Taiwan; Center of Excellence for the Oceans, National Taiwan Ocean University, Keelung City, 20224, Taiwan.
Loh JY; Faculty of Applied Sciences, UCSI University, Cheras, Kuala Lumpur, Malaysia.
Gong HY; Department of Aquaculture, National Taiwan Ocean University, Keelung, Taiwan, ROC.
Lu MW; Department of Aquaculture, National Taiwan Ocean University, Keelung, Taiwan, ROC.
Hang HT; Department of Aquaculture, National Taiwan Ocean University, Keelung, Taiwan, ROC.
Lin YL; Department of Aquaculture, National Taiwan Ocean University, Keelung, Taiwan, ROC.
Lee PT; Department of Aquaculture, National Taiwan Ocean University, Keelung, Taiwan, ROC. Electronic address: leepotsang@email.ntou.edu.tw.

Fish Shellfish Immunol ; 119: 587-601, 2021 Dec.

Article em En | MEDLINE | ID: mdl-34743023

Assuntos

Ciclídeos; Doenças dos Peixes; Proteínas Adaptadoras de Transdução de Sinal; Proteínas Adaptadoras de Transporte Vesicular; Animais; Peptídeos Antimicrobianos; Ciclídeos/genética; Ciclídeos/metabolismo; Proteínas de Peixes/genética; Proteínas de Peixes/metabolismo; Células HEK293; Humanos; Fator 88 de Diferenciação Mieloide/genética; Fator 88 de Diferenciação Mieloide/metabolismo; NF-kappa B/genética; NF-kappa B/metabolismo; Poli I-C/farmacologia

Palavras-chave

Fish TLR; Inflammation; Innate immunity; Macrophage; Tilapia

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ciclídeos / Doenças dos Peixes Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Fish Shellfish Immunol Assunto da revista: BIOLOGIA / MEDICINA VETERINARIA Ano de publicação: 2021 Tipo de documento: Article

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