Your browser doesn't support javascript.
loading
An HLA-I signature favouring KIR-educated Natural Killer cells mediates immune control of HIV in children and contrasts with the HLA-B-restricted CD8+ T-cell-mediated immune control in adults.
Vieira, Vinicius A; Adland, Emily; Malone, David F G; Martin, Maureen P; Groll, Andreas; Ansari, M Azim; Garcia-Guerrero, Maria C; Puertas, Mari C; Muenchhoff, Maximilian; Guash, Claudia Fortuny; Brander, Christian; Martinez-Picado, Javier; Bamford, Alasdair; Tudor-Williams, Gareth; Ndung'u, Thumbi; Walker, Bruce D; Ramsuran, Veron; Frater, John; Jooste, Pieter; Peppa, Dimitra; Carrington, Mary; Goulder, Philip J R.
Afiliação
  • Vieira VA; Department of Paediatrics, University of Oxford, Oxford, United Kingdom.
  • Adland E; HIV Pathogenesis Programme, Doris Duke Medical Research Institute, Nelson R Mandela School of Medicine, University of KwaZulu-Natal, Durban, South Africa.
  • Malone DFG; Department of Paediatrics, University of Oxford, Oxford, United Kingdom.
  • Martin MP; Department of Paediatrics, University of Oxford, Oxford, United Kingdom.
  • Groll A; Basic Science Program, Frederick National Laboratory for Cancer Research, National Cancer Institute, Frederick, MD and Laboratory of Integrative Cancer Immunology, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland, United States of America.
  • Ansari MA; Department of Statistics, TU Dortmund University, Dortmund, Germany.
  • Garcia-Guerrero MC; Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom.
  • Puertas MC; IrsiCaixa AIDS Research Institute, Badalona, Spain.
  • Muenchhoff M; IrsiCaixa AIDS Research Institute, Badalona, Spain.
  • Guash CF; CIBER en Enfermedades Infecciosas, Madrid, Spain.
  • Brander C; Max von Pettenkofer Institute & Gene Center, Virology, National Reference Center for Retroviruses, LMU München, Munich, Germany.
  • Martinez-Picado J; German Center for Infection Research (DZIF), partner site Munich, Munich, Germany.
  • Bamford A; Infectious Diseases and Systemic Inflammatory Response in Pediatrics, Infectious Diseases Unit, Department of Pediatrics, Sant Joan de Déu Hospital Research Foundation, Barcelona, Spain.
  • Tudor-Williams G; Center for Biomedical Network Research on Epidemiology and Public Health (CIBERESP), Madrid, Spain.
  • Ndung'u T; Department of Pediatrics, University of Barcelona, Barcelona, Spain.
  • Walker BD; Translational Research Network in Pediatric Infectious Diseases (RITIP), Madrid, Spain.
  • Ramsuran V; IrsiCaixa AIDS Research Institute, Badalona, Spain.
  • Frater J; CIBER en Enfermedades Infecciosas, Madrid, Spain.
  • Jooste P; University of Vic-Central University of Catalonia (UVic-UCC), Vic, Spain.
  • Peppa D; Catalan Institution for Research and Advanced Studies (ICREA), Barcelona, Spain.
  • Carrington M; IrsiCaixa AIDS Research Institute, Badalona, Spain.
  • Goulder PJR; CIBER en Enfermedades Infecciosas, Madrid, Spain.
PLoS Pathog ; 17(11): e1010090, 2021 11.
Article em En | MEDLINE | ID: mdl-34793581
Assuntos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Células Matadoras Naturais / Antígenos de Histocompatibilidade Classe I / Antígenos HLA-B / Infecções por HIV / HIV-1 / Linfócitos T CD8-Positivos / Receptores KIR3DL1 Tipo de estudo: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adolescent / Child / Child, preschool / Humans Idioma: En Revista: PLoS Pathog Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Reino Unido
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Células Matadoras Naturais / Antígenos de Histocompatibilidade Classe I / Antígenos HLA-B / Infecções por HIV / HIV-1 / Linfócitos T CD8-Positivos / Receptores KIR3DL1 Tipo de estudo: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adolescent / Child / Child, preschool / Humans Idioma: En Revista: PLoS Pathog Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Reino Unido