Low concentrations of 17ß-estradiol exacerbate tamoxifen resistance in breast cancer treatment through membrane estrogen receptor-mediated signaling pathways.

Xu, Zhixiang; Zhao, Dimeng; Zheng, Xianyao; Huang, Bin; Pan, Xuejun; Xia, Xueshan

Xu, Zhixiang; Zhao, Dimeng; Zheng, Xianyao; Huang, Bin; Pan, Xuejun; Xia, Xueshan.

Afiliação

Xu Z; Faculty of Environmental Science and Engineering, Kunming University of Science and Technology, Kunming, China.
Zhao D; Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming, China.
Zheng X; Faculty of Environmental Science and Engineering, Kunming University of Science and Technology, Kunming, China.
Huang B; Faculty of Environmental Science and Engineering, Kunming University of Science and Technology, Kunming, China.
Pan X; Faculty of Environmental Science and Engineering, Kunming University of Science and Technology, Kunming, China.
Xia X; Faculty of Environmental Science and Engineering, Kunming University of Science and Technology, Kunming, China.

Environ Toxicol ; 37(3): 514-526, 2022 Mar.

Article em En | MEDLINE | ID: mdl-34821461

Assuntos

Neoplasias da Mama; Tamoxifeno; Neoplasias da Mama/tratamento farmacológico; Linhagem Celular Tumoral; Resistencia a Medicamentos Antineoplásicos; Estradiol; Estrogênios; Feminino; Humanos; Células MCF-7; Receptores de Estrogênio; Transdução de Sinais

Palavras-chave

17ß-estradiol; breast cancer; estrogen receptors; in vitro; reactive oxygen species; tamoxifen resistance

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Tamoxifeno / Neoplasias da Mama Limite: Female / Humans Idioma: En Revista: Environ Toxicol Assunto da revista: SAUDE AMBIENTAL / TOXICOLOGIA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: China

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