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Deletion of pancreas-specific miR-216a reduces beta-cell mass and inhibits pancreatic cancer progression in mice.
Erener, Suheda; Ellis, Cara E; Ramzy, Adam; Glavas, Maria M; O'Dwyer, Shannon; Pereira, Sandra; Wang, Tom; Pang, Janice; Bruin, Jennifer E; Riedel, Michael J; Baker, Robert K; Webber, Travis D; Lesina, Marina; Blüher, Matthias; Algül, Hana; Kopp, Janel L; Herzig, Stephan; Kieffer, Timothy J.
Afiliação
  • Erener S; Department of Cellular & Physiological Sciences, Life Sciences Institute, University of British Columbia, Vancouver, BC, Canada.
  • Ellis CE; Institute for Diabetes and Cancer, Helmholtz Center Munich, Neuherberg, Germany.
  • Ramzy A; Department of Cellular & Physiological Sciences, Life Sciences Institute, University of British Columbia, Vancouver, BC, Canada.
  • Glavas MM; Department of Cellular & Physiological Sciences, Life Sciences Institute, University of British Columbia, Vancouver, BC, Canada.
  • O'Dwyer S; Department of Cellular & Physiological Sciences, Life Sciences Institute, University of British Columbia, Vancouver, BC, Canada.
  • Pereira S; Department of Cellular & Physiological Sciences, Life Sciences Institute, University of British Columbia, Vancouver, BC, Canada.
  • Wang T; Department of Cellular & Physiological Sciences, Life Sciences Institute, University of British Columbia, Vancouver, BC, Canada.
  • Pang J; Department of Cellular & Physiological Sciences, Life Sciences Institute, University of British Columbia, Vancouver, BC, Canada.
  • Bruin JE; Department of Cellular & Physiological Sciences, Life Sciences Institute, University of British Columbia, Vancouver, BC, Canada.
  • Riedel MJ; Department of Cellular & Physiological Sciences, Life Sciences Institute, University of British Columbia, Vancouver, BC, Canada.
  • Baker RK; Department of Biology and Institute of Biochemistry, Carleton University, Ottawa, ON, Canada.
  • Webber TD; Department of Cellular & Physiological Sciences, Life Sciences Institute, University of British Columbia, Vancouver, BC, Canada.
  • Lesina M; Department of Cellular & Physiological Sciences, Life Sciences Institute, University of British Columbia, Vancouver, BC, Canada.
  • Blüher M; Department of Cellular & Physiological Sciences, Life Sciences Institute, University of British Columbia, Vancouver, BC, Canada.
  • Algül H; Comprehensive Cancer Center Munich, Technical University of Munich, Munich, Germany.
  • Kopp JL; Helmholtz Institute for Metabolic, Obesity and Vascular Research (HI-MAG) of the Helmholtz Zentrum München at the University of Leipzig and University Hospital Leipzig, Leipzig, Germany.
  • Herzig S; Medical Department III - Endocrinology, Nephrology, Rheumatology, University of Leipzig Medical Center, Leipzig, Germany.
  • Kieffer TJ; Comprehensive Cancer Center Munich, Technical University of Munich, Munich, Germany.
Cell Rep Med ; 2(11): 100434, 2021 11 16.
Article em En | MEDLINE | ID: mdl-34841287
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Pancreáticas / Deleção de Genes / Progressão da Doença / MicroRNAs / Células Secretoras de Insulina Limite: Animals / Humans Idioma: En Revista: Cell Rep Med Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Canadá
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Pancreáticas / Deleção de Genes / Progressão da Doença / MicroRNAs / Células Secretoras de Insulina Limite: Animals / Humans Idioma: En Revista: Cell Rep Med Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Canadá