Multiomics Analysis of Spatially Distinct Stromal Cells Reveals Tumor-Induced O-Glycosylation of the CDK4-pRB Axis in Fibroblasts at the Invasive Tumor Edge.

Bouchard, Gina; Garcia-Marques, Fernando Jose; Karacosta, Loukia Georgiou; Zhang, Weiruo; Bermudez, Abel; Riley, Nicholas McIlvain; Varma, Sushama; Mehl, Lindsey Catherine; Benson, Jalen Anthony; Shrager, Joseph B; Bertozzi, Carolyn Ruth; Pitteri, Sharon J; Giaccia, Amato J; Plevritis, Sylvia Katina

Bouchard, Gina; Garcia-Marques, Fernando Jose; Karacosta, Loukia Georgiou; Zhang, Weiruo; Bermudez, Abel; Riley, Nicholas McIlvain; Varma, Sushama; Mehl, Lindsey Catherine; Benson, Jalen Anthony; Shrager, Joseph B; Bertozzi, Carolyn Ruth; Pitteri, Sharon J; Giaccia, Amato J; Plevritis, Sylvia Katina.

Afiliação

Bouchard G; Department of Biomedical Data Science, Stanford University, Stanford, California.
Garcia-Marques FJ; Department of Radiology, Canary Center for Cancer Early Detection, Palo Alto, California.
Karacosta LG; Department of Radiation Oncology, Stanford University, Stanford, California.
Zhang W; Department of Radiology, Canary Center for Cancer Early Detection, Palo Alto, California.
Bermudez A; Department of Biomedical Data Science, Stanford University, Stanford, California.
Riley NM; Department of Biomedical Data Science, Stanford University, Stanford, California.
Varma S; Department of Radiology, Canary Center for Cancer Early Detection, Palo Alto, California.
Mehl LC; Departments of Chemistry, Stanford University, Stanford, California.
Benson JA; Department of Pathology, Stanford University, Stanford, California.
Shrager JB; Department of Biomedical Data Science, Stanford University, Stanford, California.
Bertozzi CR; Department of Cardiothoracic Surgery, Stanford University, Stanford, California.
Pitteri SJ; Department of Cardiothoracic Surgery, Stanford University, Stanford, California.
Giaccia AJ; Departments of Chemistry, Stanford University, Stanford, California.
Plevritis SK; Department of Radiology, Canary Center for Cancer Early Detection, Palo Alto, California.

Cancer Res ; 82(4): 648-664, 2022 02 15.

Article em En | MEDLINE | ID: mdl-34853070

Assuntos

Fibroblastos Associados a Câncer/metabolismo; Quinase 4 Dependente de Ciclina/genética; Genômica/métodos; Neoplasias/genética; Proteômica/métodos; Proteína do Retinoblastoma/genética; Células Estromais/metabolismo; Células A549; Linhagem Celular Tumoral; Quinase 4 Dependente de Ciclina/metabolismo; Glicoproteínas/genética; Glicoproteínas/metabolismo; Glicosilação; Humanos; Invasividade Neoplásica; Neoplasias/metabolismo; Neoplasias/patologia; Fosforilação; Proteína do Retinoblastoma/metabolismo; Transdução de Sinais/genética; Transcriptoma/genética

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteína do Retinoblastoma / Células Estromais / Genômica / Proteômica / Quinase 4 Dependente de Ciclina / Fibroblastos Associados a Câncer / Neoplasias Limite: Humans Idioma: En Revista: Cancer Res Ano de publicação: 2022 Tipo de documento: Article

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