Biomaterials and stem cells as drug/gene-delivery vehicles for Parkinson's treatment: an update.
Regen Med
; 16(12): 1057-1072, 2021 11.
Article
em En
| MEDLINE
| ID: mdl-34865515
ABSTRACT
By introducing biomaterials and stem cells into Parkinson's disease (PD), therapeutic approaches have led to promising results due to facilitating brain targeting and blood-brain barrier permeation of the drugs and genes. Here, after reviewing the most recent drug- and gene-delivery vehicles including liposomes, exosomes, natural/synthetic polymeric particles/fibers, metallic/ceramic nanoparticles and microbubbles, used for Parkinson's disease treatment, the effect of stem cells as a reservoir of neurotrophic factors and exosomes is provided.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Doença de Parkinson
Limite:
Humans
Idioma:
En
Revista:
Regen Med
Ano de publicação:
2021
Tipo de documento:
Article
País de afiliação:
Irã