The PI3K/Akt/mTOR axis in colorectal cancer: Oncogenic alterations, non-coding RNAs, therapeutic opportunities, and the emerging role of nanoparticles.

Sanaei, Mohammad-Javad; Baghery Saghchy Khorasani, Ayda; Pourbagheri-Sigaroodi, Atieh; Shahrokh, Shabnam; Zali, Mohammad Reza; Bashash, Davood

Sanaei, Mohammad-Javad; Baghery Saghchy Khorasani, Ayda; Pourbagheri-Sigaroodi, Atieh; Shahrokh, Shabnam; Zali, Mohammad Reza; Bashash, Davood.

Afiliação

Sanaei MJ; Department of Hematology and Blood Banking, School of Allied Medical Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Baghery Saghchy Khorasani A; Department of Hematology, School of Medical Sciences, Tarbiat Modares University, Tehran, Iran.
Pourbagheri-Sigaroodi A; Department of Hematology and Blood Banking, School of Allied Medical Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Shahrokh S; Gastroenterology and Liver Diseases Research Center, Research Institute for Gastroenterology and Liver Diseases, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Zali MR; Gastroenterology and Liver Diseases Research Center, Research Institute for Gastroenterology and Liver Diseases, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Bashash D; Department of Hematology and Blood Banking, School of Allied Medical Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

J Cell Physiol ; 237(3): 1720-1752, 2022 03.

Article em En | MEDLINE | ID: mdl-34897682

Assuntos

Neoplasias Colorretais; Nanopartículas; Carcinogênese; Proliferação de Células; Neoplasias Colorretais/tratamento farmacológico; Neoplasias Colorretais/genética; Neoplasias Colorretais/metabolismo; Transição Epitelial-Mesenquimal; Humanos; Fosfatidilinositol 3-Quinase/metabolismo; Fosfatidilinositol 3-Quinases/metabolismo; Proteínas Proto-Oncogênicas c-akt/genética; Proteínas Proto-Oncogênicas c-akt/metabolismo; RNA não Traduzido/genética; Transdução de Sinais; Serina-Treonina Quinases TOR/genética; Serina-Treonina Quinases TOR/metabolismo

Palavras-chave

PI3K/Akt/mTOR pathway; colorectal cancer; long noncoding RNA; microRNA; predictive biomarker; prognostic biomarker

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Colorretais / Nanopartículas Limite: Humans Idioma: En Revista: J Cell Physiol Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Irã

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