Frequency of Mismatch Repair Deficiency/High Microsatellite Instability and Its Role as a Predictive Biomarker of Response to Immune Checkpoint Inhibitors in Gynecologic Cancers.

Noh, Joseph J; Kim, Min Kyu; Choi, Min Chul; Lee, Jeong-Won; Park, Hyun; Jung, Sang Geun; Joo, Won Duk; Song, Seung Hun; Lee, Chan

Noh, Joseph J; Kim, Min Kyu; Choi, Min Chul; Lee, Jeong-Won; Park, Hyun; Jung, Sang Geun; Joo, Won Duk; Song, Seung Hun; Lee, Chan.

Afiliação

Noh JJ; Gynecologic Cancer Center, Department of Obstetrics and Gynecology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Kim MK; Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Samsung Changwon Hospital, Sungkyunkwan University School of Medicine, Changwon, Korea.
Choi MC; Comprehensive Gynecologic Cancer Center, CHA Bundang Medical Center, CHA University, Seongnam, Korea.
Lee JW; Gynecologic Cancer Center, Department of Obstetrics and Gynecology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Park H; Comprehensive Gynecologic Cancer Center, CHA Bundang Medical Center, CHA University, Seongnam, Korea.
Jung SG; Comprehensive Gynecologic Cancer Center, CHA Bundang Medical Center, CHA University, Seongnam, Korea.
Joo WD; Comprehensive Gynecologic Cancer Center, CHA Bundang Medical Center, CHA University, Seongnam, Korea.
Song SH; Comprehensive Gynecologic Cancer Center, CHA Bundang Medical Center, CHA University, Seongnam, Korea.
Lee C; Comprehensive Gynecologic Cancer Center, CHA Bundang Medical Center, CHA University, Seongnam, Korea.

Cancer Res Treat ; 54(4): 1200-1208, 2022 Oct.

Article em En | MEDLINE | ID: mdl-34902958

Assuntos

Neoplasias do Endométrio; Neoplasias dos Genitais Femininos; Neoplasias do Colo do Útero; Neoplasias Uterinas; Biomarcadores; Neoplasias Encefálicas; Neoplasias Colorretais; Reparo de Erro de Pareamento de DNA; Proteínas de Ligação a DNA/genética; Neoplasias do Endométrio/tratamento farmacológico; Neoplasias do Endométrio/genética; Feminino; Neoplasias dos Genitais Femininos/tratamento farmacológico; Neoplasias dos Genitais Femininos/genética; Humanos; Inibidores de Checkpoint Imunológico; Instabilidade de Microssatélites; Endonuclease PMS2 de Reparo de Erro de Pareamento/genética; Proteína 1 Homóloga a MutL/genética; Proteína 2 Homóloga a MutS/genética; Recidiva Local de Neoplasia; Síndromes Neoplásicas Hereditárias; Neoplasias do Colo do Útero/tratamento farmacológico; Neoplasias do Colo do Útero/genética

Palavras-chave

Gynecologic neoplasms; Immune checkpoint inhibitors; Microsatellite instability; Mismatch repair; Recurrence

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Uterinas / Neoplasias do Colo do Útero / Neoplasias do Endométrio / Neoplasias dos Genitais Femininos Tipo de estudo: Clinical_trials / Prognostic_studies / Risk_factors_studies Limite: Female / Humans Idioma: En Revista: Cancer Res Treat Ano de publicação: 2022 Tipo de documento: Article

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