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EZH2 Inhibition Compromises α4-1BB-Mediated Antitumor Efficacy by Reducing the Survival and Effector Programming of CD8+ T Cells.
Stairiker, Christopher J; Pfister, Sophia Xiao; Hendrickson, Eleanore; Yang, Wenjing; Xie, Tao; Lee, Catherine; Zhang, Haikuo; Dillon, Christopher; Thomas, Graham D; Salek-Ardakani, Shahram.
Afiliação
  • Stairiker CJ; Cancer Immunology Discovery, Worldwide Research, Development Medical, Pfizer Inc., San Diego, CA, United States.
  • Pfister SX; Cancer Immunology Discovery, Worldwide Research, Development Medical, Pfizer Inc., San Diego, CA, United States.
  • Hendrickson E; Translational Sciences, Worldwide Research, Development Medical, Pfizer Inc., San Diego, CA, United States.
  • Yang W; Computational Biology, Worldwide Research, Development Medical, Pfizer Inc., San Diego, CA, United States.
  • Xie T; Computational Biology, Worldwide Research, Development Medical, Pfizer Inc., San Diego, CA, United States.
  • Lee C; Translational Sciences, Worldwide Research, Development Medical, Pfizer Inc., San Diego, CA, United States.
  • Zhang H; Translational Sciences, Worldwide Research, Development Medical, Pfizer Inc., San Diego, CA, United States.
  • Dillon C; Translational Sciences, Worldwide Research, Development Medical, Pfizer Inc., San Diego, CA, United States.
  • Thomas GD; Cancer Immunology Discovery, Worldwide Research, Development Medical, Pfizer Inc., San Diego, CA, United States.
  • Salek-Ardakani S; Cancer Immunology Discovery, Worldwide Research, Development Medical, Pfizer Inc., San Diego, CA, United States.
Front Immunol ; 12: 770080, 2021.
Article em En | MEDLINE | ID: mdl-34925340
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Linfócitos T CD8-Positivos / Inibidores Enzimáticos / Membro 9 da Superfamília de Receptores de Fatores de Necrose Tumoral / Proteína Potenciadora do Homólogo 2 de Zeste / Anticorpos Monoclonais / Neoplasias Experimentais Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Front Immunol Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
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PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Linfócitos T CD8-Positivos / Inibidores Enzimáticos / Membro 9 da Superfamília de Receptores de Fatores de Necrose Tumoral / Proteína Potenciadora do Homólogo 2 de Zeste / Anticorpos Monoclonais / Neoplasias Experimentais Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Front Immunol Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos