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SF3B1 mutant-induced missplicing of MAP3K7 causes anemia in myelodysplastic syndromes.
Lieu, Yen K; Liu, Zhaoqi; Ali, Abdullah M; Wei, Xin; Penson, Alex; Zhang, Jian; An, Xiuli; Rabadan, Raul; Raza, Azra; Manley, James L; Mukherjee, Siddhartha.
Afiliação
  • Lieu YK; Department of Biological Sciences, Columbia University, New York, NY 10027; ylieu6@gmail.com jlm2@columbia.edu sm3252@cumc.columbia.edu.
  • Liu Z; Irving Cancer Research Center, Columbia University, New York, NY 10032.
  • Ali AM; Chinese Academy of Sciences Key Laboratory of Genomic and Precision Medicine, Beijing Institute of Genomics, Chinese Academy of Sciences 100101 Beijing, China.
  • Wei X; Department of Systems Biology, Columbia University, New York, NY 10032.
  • Penson A; Department of Biomedical Informatics, Columbia University, New York, NY 10032.
  • Zhang J; Program for Mathematical Genomics, Columbia University, New York, NY 10032.
  • An X; Division of Hematology and Oncology, Department of Medicine, Columbia University, New York, NY 10032.
  • Rabadan R; Laboratory of Membrane Biology, New York Blood Center, New York, NY 10065.
  • Raza A; Department of Anesthesiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450008, China.
  • Manley JL; Department of Systems Biology, Columbia University, New York, NY 10032.
  • Mukherjee S; Department of Biomedical Informatics, Columbia University, New York, NY 10032.
Proc Natl Acad Sci U S A ; 119(1)2022 01 04.
Article em En | MEDLINE | ID: mdl-34930825
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fosfoproteínas / Síndromes Mielodisplásicas / MAP Quinase Quinase Quinases / Sistema de Sinalização das MAP Quinases / Eritropoese / Fatores de Processamento de RNA / Anemia / Mutação Tipo de estudo: Etiology_studies Limite: Humans Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2022 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fosfoproteínas / Síndromes Mielodisplásicas / MAP Quinase Quinase Quinases / Sistema de Sinalização das MAP Quinases / Eritropoese / Fatores de Processamento de RNA / Anemia / Mutação Tipo de estudo: Etiology_studies Limite: Humans Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2022 Tipo de documento: Article