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Loss of a newly discovered microRNA in Chinese hamster ovary cells leads to upregulation of N-glycolylneuraminic acid sialylation on monoclonal antibodies.
Fischer, Simon; Mathias, Sven; Stadermann, Anna; Yang, Shumin; Schmieder, Valerie; Zeh, Nikolas; Schmidt, Nicoletta; Richter, Patrick; Wright, Sara; Zimmermann, Eike; Ley, Yan; van der Meer, Julia; Hartsch, Thomas; Bernloehr, Christian; Otte, Kerstin; Bradl, Harald; Gamer, Martin; Schulz, Patrick.
Afiliação
  • Fischer S; Cell Line Development, Bioprocess Development Biologicals, Boehringer Ingelheim GmbH & Co. KG, Biberach, Germany.
  • Mathias S; Early Stage Bioprocess Development, Bioprocess Development Biologicals, Boehringer Ingelheim GmbH & Co. KG, Biberach, Germany.
  • Stadermann A; Institute of Applied Biotechnology, University of Applied Sciences, Biberach, Germany.
  • Yang S; Cell Line Development, Bioprocess Development Biologicals, Boehringer Ingelheim GmbH & Co. KG, Biberach, Germany.
  • Schmieder V; Process Science, Boehringer Ingelheim Fremont Inc., Fremont, California, USA.
  • Zeh N; Cell Line Development, Bioprocess Development Biologicals, Boehringer Ingelheim GmbH & Co. KG, Biberach, Germany.
  • Schmidt N; Cell Line Development, Bioprocess Development Biologicals, Boehringer Ingelheim GmbH & Co. KG, Biberach, Germany.
  • Richter P; Cell Line Development, Bioprocess Development Biologicals, Boehringer Ingelheim GmbH & Co. KG, Biberach, Germany.
  • Wright S; Cell Line Development, Bioprocess Development Biologicals, Boehringer Ingelheim GmbH & Co. KG, Biberach, Germany.
  • Zimmermann E; Analytical Science, Boehringer Ingelheim Fremont Inc., Fremont, California, USA.
  • Ley Y; Analytical Science, Boehringer Ingelheim Fremont Inc., Fremont, California, USA.
  • van der Meer J; Analytical Science, Boehringer Ingelheim Fremont Inc., Fremont, California, USA.
  • Hartsch T; Genedata AG, Basel, Switzerland.
  • Bernloehr C; Genedata AG, Basel, Switzerland.
  • Otte K; Early Stage Bioprocess Development, Bioprocess Development Biologicals, Boehringer Ingelheim GmbH & Co. KG, Biberach, Germany.
  • Bradl H; Institute of Applied Biotechnology, University of Applied Sciences, Biberach, Germany.
  • Gamer M; Protein Science, Bioprocess & Analytical Development, Boehringer Ingelheim GmbH & Co. KG, Biberach, Germany.
  • Schulz P; Cell Line Development, Bioprocess Development Biologicals, Boehringer Ingelheim GmbH & Co. KG, Biberach, Germany.
Biotechnol Bioeng ; 119(3): 832-844, 2022 03.
Article em En | MEDLINE | ID: mdl-34935124

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: MicroRNAs / Anticorpos Monoclonais Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Biotechnol Bioeng Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Alemanha

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: MicroRNAs / Anticorpos Monoclonais Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Biotechnol Bioeng Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Alemanha