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Safety, efficacy, and tolerability of memantine for cognitive and adaptive outcome measures in adolescents and young adults with Down syndrome: a randomised, double-blind, placebo-controlled phase 2 trial.
Costa, Alberto C S; Brandão, Ana C; Boada, Richard; Barrionuevo, Veridiana L; Taylor, Hudson G; Roth, Elizabeth; Stasko, Melissa R; Johnson, Mark W; Assir, Fernanda F; Roberto, Maria P; Salmona, Patrícia; Abreu-Silveira, Guilherme; Bederman, Ilya; Prendergast, Erin; Hüls, Anke; Abrishamcar, Sarina; Mustacchi, Zan; Scheidemantel, Thomas; Roizen, Nancy J; Ruedrich, Stephen.
Afiliação
  • Costa ACS; Department of Pediatrics, School of Medicine, Case Western Reserve University, Cleveland, OH, USA; Department of Psychiatry, School of Medicine, Case Western Reserve University, Cleveland, OH, USA. Electronic address: alberto.costa@case.edu.
  • Brandão AC; Hospital Israelita Albert Einstein, São Paulo, Brazil.
  • Boada R; Department of Pediatrics, School of Medicine, University of Colorado Aurora, CO, USA.
  • Barrionuevo VL; São Paulo Center for Clinical Studies and Research-CEPEC-SP, São Paulo, Brazil.
  • Taylor HG; Center for Biobehavioral Health, Nationwide Children's Hospital Research Institute, Ohio State University, Columbus, OH, USA.
  • Roth E; Department of Pediatrics, School of Medicine, Case Western Reserve University, Cleveland, OH, USA.
  • Stasko MR; Department of Pediatrics, School of Medicine, Case Western Reserve University, Cleveland, OH, USA.
  • Johnson MW; Department of Pediatrics, School of Medicine, Case Western Reserve University, Cleveland, OH, USA.
  • Assir FF; Hospital Israelita Albert Einstein, São Paulo, Brazil.
  • Roberto MP; Hospital Israelita Albert Einstein, São Paulo, Brazil.
  • Salmona P; São Paulo Center for Clinical Studies and Research-CEPEC-SP, São Paulo, Brazil.
  • Abreu-Silveira G; Hospital Israelita Albert Einstein, São Paulo, Brazil.
  • Bederman I; Department of Genetics and Genome Sciences, School of Medicine, Case Western Reserve University, Cleveland, OH, USA.
  • Prendergast E; Department of Genetics and Genome Sciences, School of Medicine, Case Western Reserve University, Cleveland, OH, USA.
  • Hüls A; Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA, USA; Gangarosa Department of Environmental Health, Rollins School of Public Health, Emory University, Atlanta, GA, USA.
  • Abrishamcar S; Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA, USA.
  • Mustacchi Z; São Paulo Center for Clinical Studies and Research-CEPEC-SP, São Paulo, Brazil.
  • Scheidemantel T; Department of Psychiatry, School of Medicine, Case Western Reserve University, Cleveland, OH, USA.
  • Roizen NJ; Department of Pediatrics, School of Medicine, Case Western Reserve University, Cleveland, OH, USA.
  • Ruedrich S; Department of Psychiatry, School of Medicine, Case Western Reserve University, Cleveland, OH, USA.
Lancet Neurol ; 21(1): 31-41, 2022 01.
Article em En | MEDLINE | ID: mdl-34942135
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Memantina / Síndrome de Down Tipo de estudo: Clinical_trials / Guideline / Prognostic_studies Limite: Adolescent / Adult / Female / Humans / Male Idioma: En Revista: Lancet Neurol Assunto da revista: NEUROLOGIA Ano de publicação: 2022 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Memantina / Síndrome de Down Tipo de estudo: Clinical_trials / Guideline / Prognostic_studies Limite: Adolescent / Adult / Female / Humans / Male Idioma: En Revista: Lancet Neurol Assunto da revista: NEUROLOGIA Ano de publicação: 2022 Tipo de documento: Article