Role of FGF Receptors and Their Pathways in Adrenocortical Tumors and Possible Therapeutic Implications.

Sbiera, Iuliu; Kircher, Stefan; Altieri, Barbara; Lenz, Kerstin; Hantel, Constanze; Fassnacht, Martin; Sbiera, Silviu; Kroiss, Matthias

Sbiera, Iuliu; Kircher, Stefan; Altieri, Barbara; Lenz, Kerstin; Hantel, Constanze; Fassnacht, Martin; Sbiera, Silviu; Kroiss, Matthias.

Afiliação

Sbiera I; Department of Internal Medicine I, Division of Endocrinology and Diabetes, University Hospital, University of Würzburg, Würzburg, Germany.
Kircher S; Institute of Pathology, University of Würzburg, Würzburg, Germany.
Altieri B; Department of Internal Medicine I, Division of Endocrinology and Diabetes, University Hospital, University of Würzburg, Würzburg, Germany.
Lenz K; Department of Internal Medicine I, Division of Endocrinology and Diabetes, University Hospital, University of Würzburg, Würzburg, Germany.
Hantel C; Department of Endocrinology, Diabetology and Clinical Nutrition, University Hospital Zürich (USZ) and University of Zürich (UZH), Zürich, Switzerland.
Fassnacht M; Medizinische Klinik und Poliklinik III, University Hospital Carl Gustav Carus Dresden, Dresden, Germany.
Sbiera S; Department of Internal Medicine I, Division of Endocrinology and Diabetes, University Hospital, University of Würzburg, Würzburg, Germany.
Kroiss M; Clinical Chemistry and Laboratory Medicine, University Hospital, University of Würzburg, Würzburg, Germany.

Front Endocrinol (Lausanne) ; 12: 795116, 2021.

Article em En | MEDLINE | ID: mdl-34956100

Assuntos

Neoplasias do Córtex Suprarrenal/metabolismo; Carcinoma Adrenocortical/metabolismo; Biomarcadores Tumorais/biossíntese; Receptor Tipo 1 de Fator de Crescimento de Fibroblastos/biossíntese; Receptor Tipo 4 de Fator de Crescimento de Fibroblastos/biossíntese; Neoplasias do Córtex Suprarrenal/genética; Neoplasias do Córtex Suprarrenal/mortalidade; Carcinoma Adrenocortical/genética; Carcinoma Adrenocortical/mortalidade; Adulto; Biomarcadores Tumorais/genética; Feminino; Humanos; Masculino; Pessoa de Meia-Idade; Reação em Cadeia da Polimerase em Tempo Real/métodos; Receptor Tipo 1 de Fator de Crescimento de Fibroblastos/genética; Receptor Tipo 4 de Fator de Crescimento de Fibroblastos/genética; Taxa de Sobrevida/tendências

Palavras-chave

FGF-pathway; FGFR; RNA Expression; RNAScope; adrenocortical tumors; normal adrenal glands; patient survival; unsupervised clustering

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Biomarcadores Tumorais / Neoplasias do Córtex Suprarrenal / Carcinoma Adrenocortical / Receptor Tipo 1 de Fator de Crescimento de Fibroblastos / Receptor Tipo 4 de Fator de Crescimento de Fibroblastos Tipo de estudo: Prognostic_studies Limite: Adult / Female / Humans / Male / Middle aged Idioma: En Revista: Front Endocrinol (Lausanne) Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Alemanha

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