[Research progress of respiratory syncytial virus (RSV) infection and respiratory diseases in infancy].
Sheng Li Xue Bao
; 73(6): 1043-1053, 2021 Dec 25.
Article
em Zh
| MEDLINE
| ID: mdl-34961879
ABSTRACT
Lower respiratory tract infection (LRTI) induced by respiratory syncytial virus (RSV) is an important cause of hospitalization for infants. Compared with adults, infants are more likely to cause serious respiratory diseases after RSV infection due to the specific immature airway structure and immune system. The balance of immune resistance and immune tolerance of the host is critical to effective virus clearance and disease control. This paper reviews the relationship between RSV infection and respiratory diseases in infancy, the influence factors of the high pathogenicity of RSV infection in early life, as well as the research progress of anti-RSV therapy, and expands the specific molecular events regulating immune resistance and immune tolerance. We expect to present new ideas for the prevention and treatment of RSV-related respiratory diseases in clinical practice.
Buscar no Google
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Transtornos Respiratórios
/
Infecções Respiratórias
/
Infecções por Vírus Respiratório Sincicial
Limite:
Humans
/
Infant
Idioma:
Zh
Revista:
Sheng Li Xue Bao
Ano de publicação:
2021
Tipo de documento:
Article
País de afiliação:
China