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Penfluridol targets acid sphingomyelinase to inhibit TNF signaling and is therapeutic against inflammatory autoimmune diseases.
Chen, Yue-Hong; Liu, Rong-Han; Cui, Ya-Zhou; Hettinghouse, Aubryanna; Fu, Wen-Yu; Zhang, Lei; Zhang, Chen; Liu, Chuan-Ju.
Afiliação
  • Chen YH; Department of Orthopaedic Surgery, New York University Grossman School of Medicine, Rm 1608, HJD, 301 East 17th Street, New York, NY, 10003, USA.
  • Liu RH; Department of Rheumatology and Immunology, West China Hospital, Sichuan University, Chengdu, 610000, China.
  • Cui YZ; Department of Orthopaedic Surgery, New York University Grossman School of Medicine, Rm 1608, HJD, 301 East 17th Street, New York, NY, 10003, USA.
  • Hettinghouse A; Department of Orthopaedic Surgery, New York University Grossman School of Medicine, Rm 1608, HJD, 301 East 17th Street, New York, NY, 10003, USA.
  • Fu WY; Department of Orthopaedic Surgery, New York University Grossman School of Medicine, Rm 1608, HJD, 301 East 17th Street, New York, NY, 10003, USA.
  • Zhang L; Department of Orthopaedic Surgery, New York University Grossman School of Medicine, Rm 1608, HJD, 301 East 17th Street, New York, NY, 10003, USA.
  • Zhang C; Department of Orthopaedic Surgery, New York University Grossman School of Medicine, Rm 1608, HJD, 301 East 17th Street, New York, NY, 10003, USA.
  • Liu CJ; Department of Orthopaedic Surgery, New York University Grossman School of Medicine, Rm 1608, HJD, 301 East 17th Street, New York, NY, 10003, USA.
Arthritis Res Ther ; 24(1): 27, 2022 01 19.
Article em En | MEDLINE | ID: mdl-35045889

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Penfluridol / Doenças Autoimunes Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Arthritis Res Ther Assunto da revista: REUMATOLOGIA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Penfluridol / Doenças Autoimunes Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Arthritis Res Ther Assunto da revista: REUMATOLOGIA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos