4-octyl Itaconate inhibits lipopolysaccharide (LPS)-induced osteoarthritis via activating Nrf2 signalling pathway.

Zhang, Qingchen; Bai, Xiaohui; Wang, Rongrong; Zhao, Hao; Wang, Lili; Liu, Jingwen; Li, Ming; Chen, Zheng; Wang, Zejun; Li, Lianxin; Wang, Dawei

4-octyl Itaconate inhibits lipopolysaccharide (LPS)-induced osteoarthritis via activating Nrf2 signalling pathway.

Zhang, Qingchen; Bai, Xiaohui; Wang, Rongrong; Zhao, Hao; Wang, Lili; Liu, Jingwen; Li, Ming; Chen, Zheng; Wang, Zejun; Li, Lianxin; Wang, Dawei.

Afiliação

Zhang Q; Department of Orthopaedics, Shandong Provincial Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China.
Bai X; Department of Orthopaedics, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, China.
Wang R; Department of Clinical Laboratory, Shandong Provincial Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China.
Zhao H; Department of Clinical Laboratory, Shandong Provincial Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China.
Wang L; Department of Clinical Laboratory, Shandong Provincial Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China.
Liu J; Department of Clinical Laboratory, Shandong Provincial Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China.
Li M; Department of Clinical Laboratory, Shandong Provincial Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China.
Chen Z; Department of Clinical Laboratory, Shandong Provincial Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China.
Wang Z; Department of Orthopaedics, Shandong Provincial Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China.
Li L; Department of Orthopaedics, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, China.
Wang D; Department of Clinical Laboratory, Shandong Provincial Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China.

J Cell Mol Med ; 26(5): 1515-1529, 2022 03.

Article em En | MEDLINE | ID: mdl-35068055

Assuntos

Fator 2 Relacionado a NF-E2; Osteoartrite; Animais; Apoptose; Condrócitos/metabolismo; Lipopolissacarídeos/farmacologia; Camundongos; Fator 2 Relacionado a NF-E2/genética; Fator 2 Relacionado a NF-E2/metabolismo; Osteoartrite/induzido quimicamente; Osteoartrite/tratamento farmacológico; Osteoartrite/genética; Transdução de Sinais; Succinatos

Palavras-chave

4-octyl itaconate; Nrf2 signalling pathway; lipopolysaccharide; osteoarthritis

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Osteoartrite / Fator 2 Relacionado a NF-E2 Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: J Cell Mol Med Assunto da revista: BIOLOGIA MOLECULAR Ano de publicação: 2022 Tipo de documento: Article País de afiliação: China

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