Comprehensive Analysis of CD4<sup>+</sup> T Cell Response Cross-Reactive to SARS-CoV-2 Antigens at the Single Allele Level of HLA Class II.

Hyun, You-Seok; Lee, Yong-Hun; Jo, Hyeong-A; Baek, In-Cheol; Kim, Sun-Mi; Sohn, Hyun-Jung; Kim, Tai-Gyu

Comprehensive Analysis of CD4⁺ T Cell Response Cross-Reactive to SARS-CoV-2 Antigens at the Single Allele Level of HLA Class II.

Hyun, You-Seok; Lee, Yong-Hun; Jo, Hyeong-A; Baek, In-Cheol; Kim, Sun-Mi; Sohn, Hyun-Jung; Kim, Tai-Gyu.

Afiliação

Hyun YS; Department of Microbiology, College of Medicine, The Catholic University of Korea, Seoul, South Korea.
Lee YH; Department of Biomedicine and Health Sciences, College of Medicine, The Catholic University of Korea, Seoul, South Korea.
Jo HA; Department of Microbiology, College of Medicine, The Catholic University of Korea, Seoul, South Korea.
Baek IC; Department of Biomedicine and Health Sciences, College of Medicine, The Catholic University of Korea, Seoul, South Korea.
Kim SM; Department of Microbiology, College of Medicine, The Catholic University of Korea, Seoul, South Korea.
Sohn HJ; Department of Biomedicine and Health Sciences, College of Medicine, The Catholic University of Korea, Seoul, South Korea.
Kim TG; Catholic Hematopoietic Stem Cell Bank, College of Medicine, The Catholic University of Korea, Seoul, South Korea.

Front Immunol ; 12: 774491, 2021.

Article em En | MEDLINE | ID: mdl-35069546

Assuntos

Alelos; Antígenos Virais/imunologia; Linfócitos T CD4-Positivos/imunologia; COVID-19/imunologia; Genes MHC da Classe II; Antígenos HLA-D/genética; SARS-CoV-2/imunologia; Adulto; Células Apresentadoras de Antígenos/imunologia; Doadores de Sangue; COVID-19/virologia; Células Cultivadas; Reações Cruzadas; ELISPOT/métodos; Feminino; Antígenos HLA-D/imunologia; Voluntários Saudáveis; Humanos; Alótipos de Imunoglobulina/imunologia; Masculino; Adulto Jovem

Palavras-chave

CD4+ T cells; HLA-DP; HLA-DQ; HLA-DR; MHC class II alleles; SARS-CoV-2; cross-reactive T cells; immunodominance

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Linfócitos T CD4-Positivos / Antígenos HLA-D / Genes MHC da Classe II / Alelos / SARS-CoV-2 / COVID-19 / Antígenos Virais Limite: Adult / Female / Humans / Male Idioma: En Revista: Front Immunol Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Coréia do Sul

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