Escaping stochastic extinction of mutant virus: Temporal pattern of emergence of drug resistance within a host.

Hayashi, Rena; Iwami, Shingo; Iwasa, Yoh

Hayashi, Rena; Iwami, Shingo; Iwasa, Yoh.

Afiliação

Hayashi R; Department of Biology, Kyushu University, 744 Motooka, Nishi-ku, Fukuoka 819-0395, Japan.
Iwami S; iBLab, Division of Biological Sciences, Graduate School of Science, Nagoya University, Furo-cho, Chikusa-ku, Nagoya 464-8602, Japan; Institute of Mathematics for Industry, Kyushu University, Fukuoka 819-039, Japan; ASHBi, Kyoto University, Yoshida-konoe-cho, Sakyo-ku, Kyoto 606-8501, Japan; iTHEMS, RIKEN, Hirosawa 2-1, Wako. Saitama 351-0198, Japan; NEXT-Ganken Program, Japanese Foundation for Cancer Research, 3-8-31 Ariake, Koto-ku, Tokyo 135-8550, Japan; Science Groove Inc., Fukuoka 810-0041,
Iwasa Y; Department of Biology, Kyushu University, 744 Motooka, Nishi-ku, Fukuoka 819-0395, Japan; Institute of Freshwater Biology, Nagano University, 1088 Komaki, Ueda Nagano 386-0031, Japan. Electronic address: yohiwasa@kyudai.jp.

J Theor Biol ; 537: 111029, 2022 03 21.

Article em En | MEDLINE | ID: mdl-35077709

Assuntos

Vírus; Antivirais/farmacologia; Resistência a Medicamentos; Humanos; Mutação; Probabilidade; Processos Estocásticos

Palavras-chave

Drug resistance; Escape mutant; Time-dependent branching processes; Viral dynamics

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Vírus Limite: Humans Idioma: En Revista: J Theor Biol Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Japão

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google