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A simple quinoline salt derivative is active in vitro against Plasmodiumfalciparum asexual blood stages and inhibits the development of cerebral malaria in murine model.
Bezerra Bellei, Jessica Correa; Glanzmann, Nícolas; Carpinter, Bárbara Albuquerque; Renhe, Daniela Chaves; Marques, Carolina Brandi; Azevedo, Marina Rocha; Barreto, Livia Maria; Rocha, Vinicius Novaes; Karine da Costa Nunes, Isabelle; Gualberto Pereira, Henrique Marcelo; Coimbra, Elaine Soares; Ferraz Coelho, Eduardo Antônio; David da Silva, Adilson; de Pilla Varotti, Fernando; Gorza Scopel, Kézia Katiani.
Afiliação
  • Bezerra Bellei JC; Research Center Parasitology. Departament of Parasitology, Microbiology and Immunology. Federal University of Juiz de Fora, Juiz de Fora/MG 36.036-900, Brazil.
  • Glanzmann N; Department of Chemistry, Institute of Exact Sciences, Federal University of Juiz de Fora, Juiz de Fora/MG 36.036-900, Brazil.
  • Carpinter BA; Research Center Parasitology. Departament of Parasitology, Microbiology and Immunology. Federal University of Juiz de Fora, Juiz de Fora/MG 36.036-900, Brazil.
  • Renhe DC; Research Center Parasitology. Departament of Parasitology, Microbiology and Immunology. Federal University of Juiz de Fora, Juiz de Fora/MG 36.036-900, Brazil.
  • Marques CB; Research Center Parasitology. Departament of Parasitology, Microbiology and Immunology. Federal University of Juiz de Fora, Juiz de Fora/MG 36.036-900, Brazil.
  • Azevedo MR; Research Center Parasitology. Departament of Parasitology, Microbiology and Immunology. Federal University of Juiz de Fora, Juiz de Fora/MG 36.036-900, Brazil.
  • Barreto LM; Research Center Parasitology. Departament of Parasitology, Microbiology and Immunology. Federal University of Juiz de Fora, Juiz de Fora/MG 36.036-900, Brazil.
  • Rocha VN; Research Center of Pathology and Veterinary Histology. Departament of Veterinary Medicine /Federal University of Juiz de Fora, Juiz de Fora/MG 36.036-900, Brazil.
  • Karine da Costa Nunes I; Technological Development Support Laboratory, Chemistry Hub, Federal University of Rio de Janeiro, Rio de Janeiro/RJ 21.941-598, Brazil.
  • Gualberto Pereira HM; Technological Development Support Laboratory, Chemistry Hub, Federal University of Rio de Janeiro, Rio de Janeiro/RJ 21.941-598, Brazil.
  • Coimbra ES; Research Center Parasitology. Departament of Parasitology, Microbiology and Immunology. Federal University of Juiz de Fora, Juiz de Fora/MG 36.036-900, Brazil.
  • Ferraz Coelho EA; Postgraduation Program in Health Sciences, Infectology and Tropical Medicine, Faculty of Medicine, Federal University of Minas Gerais, Av. Alfredo Balena, 190, 30130-100, Belo Horizonte, Minas Gerais, Brazil.
  • David da Silva A; Department of Chemistry, Institute of Exact Sciences, Federal University of Juiz de Fora, Juiz de Fora/MG 36.036-900, Brazil.
  • de Pilla Varotti F; Research Center on Biological Chemistry (NQBio)/Federal University of São João Del Rei, Divinópolis, MG, Brazil. Electronic address: varotti@ufsj.edu.br.
  • Gorza Scopel KK; Research Center Parasitology. Departament of Parasitology, Microbiology and Immunology. Federal University of Juiz de Fora, Juiz de Fora/MG 36.036-900, Brazil. Electronic address: keziagscopel@gmail.com.
Chem Biol Interact ; 355: 109848, 2022 Mar 01.
Article em En | MEDLINE | ID: mdl-35149084
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Plasmodium falciparum / Quinolinas / Malária Cerebral / Antimaláricos Limite: Animals / Female / Humans Idioma: En Revista: Chem Biol Interact Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Brasil
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Plasmodium falciparum / Quinolinas / Malária Cerebral / Antimaláricos Limite: Animals / Female / Humans Idioma: En Revista: Chem Biol Interact Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Brasil