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Inhibition of carnitine palmitoyltransferase 1A in hepatic stellate cells protects against fibrosis.
Fondevila, Marcos F; Fernandez, Uxia; Heras, Violeta; Parracho, Tamara; Gonzalez-Rellan, Maria J; Novoa, Eva; Porteiro, Begoña; Alonso, Cristina; Mayo, Rebeca; da Silva Lima, Natalia; Iglesias, Cristina; Filliol, Aveline A; Senra, Ana; Delgado, Teresa C; Woodhoo, Ashwin; Herrero, Laura; Serra, Dolors; Prevot, Vincent; Schwaninger, Markus; López, Miguel; Dieguez, Carlos; Millet, Oscar; Mato, Jose M; Cubero, Francisco J; Varela-Rey, Marta; Iruzubieta, Paula; Crespo, Javier; Martinez-Chantar, Maria L; Schwabe, Robert F; Nogueiras, Ruben.
Afiliação
  • Fondevila MF; Department of Physiology, CIMUS, University of Santiago de Compostela-Instituto de Investigación Sanitaria, Santiago de Compostela, Spain; CIBER Fisiopatología de la Obesidad y Nutrición (CIBEROBN), Instituto de Salud Carlos III, Spain. Electronic address: marcos.fernandez.fondevila@gmail.com.
  • Fernandez U; Department of Physiology, CIMUS, University of Santiago de Compostela-Instituto de Investigación Sanitaria, Santiago de Compostela, Spain; CIBER Fisiopatología de la Obesidad y Nutrición (CIBEROBN), Instituto de Salud Carlos III, Spain.
  • Heras V; Department of Physiology, CIMUS, University of Santiago de Compostela-Instituto de Investigación Sanitaria, Santiago de Compostela, Spain.
  • Parracho T; Department of Physiology, CIMUS, University of Santiago de Compostela-Instituto de Investigación Sanitaria, Santiago de Compostela, Spain.
  • Gonzalez-Rellan MJ; Department of Physiology, CIMUS, University of Santiago de Compostela-Instituto de Investigación Sanitaria, Santiago de Compostela, Spain.
  • Novoa E; Department of Physiology, CIMUS, University of Santiago de Compostela-Instituto de Investigación Sanitaria, Santiago de Compostela, Spain.
  • Porteiro B; Department of Physiology, CIMUS, University of Santiago de Compostela-Instituto de Investigación Sanitaria, Santiago de Compostela, Spain.
  • Alonso C; OWL Metabolomics, Technology Park of Bizkaia, Derio, Bizkaia, Spain.
  • Mayo R; OWL Metabolomics, Technology Park of Bizkaia, Derio, Bizkaia, Spain.
  • da Silva Lima N; Department of Physiology, CIMUS, University of Santiago de Compostela-Instituto de Investigación Sanitaria, Santiago de Compostela, Spain.
  • Iglesias C; Department of Physiology, CIMUS, University of Santiago de Compostela-Instituto de Investigación Sanitaria, Santiago de Compostela, Spain.
  • Filliol AA; Department of Medicine, Columbia University, New York, NY, USA.
  • Senra A; Department of Physiology, CIMUS, University of Santiago de Compostela-Instituto de Investigación Sanitaria, Santiago de Compostela, Spain.
  • Delgado TC; Liver Disease Lab, Center for Cooperative Research in Biosciences (CIC bioGUNE), Basque Research and Technology Alliance (BRTA), 48160 Derio, Bizkaia, Spain; CIBER Enfermedades Hepáticas y Digestivas (CIBERehd), Spain.
  • Woodhoo A; Gene Regulatory Control in Disease, CIMUS, University of Santiago de Compostela, Santiago de Compostela, Spain.
  • Herrero L; CIBER Fisiopatología de la Obesidad y Nutrición (CIBEROBN), Instituto de Salud Carlos III, Spain; Department of Biochemistry and Physiology, School of Pharmacy and Food Sciences, Institut de Biomedicina de la Universitat de Barcelona (IBUB), Barcelona, Spain.
  • Serra D; CIBER Fisiopatología de la Obesidad y Nutrición (CIBEROBN), Instituto de Salud Carlos III, Spain; Department of Biochemistry and Physiology, School of Pharmacy and Food Sciences, Institut de Biomedicina de la Universitat de Barcelona (IBUB), Barcelona, Spain.
  • Prevot V; Univ. Lille, Inserm, CHU Lille, Laboratory of Development and Plasticity of the Neuroendocrine Brain, Lille Neuroscience & Cognition, UMR-S 1172, European Genomic Institute for Diabetes (EGID), F-59000 Lille, France.
  • Schwaninger M; University of Lübeck, Institute for Experimental and Clinical Pharmacology and Toxicology, Lübeck, Germany.
  • López M; Department of Physiology, CIMUS, University of Santiago de Compostela-Instituto de Investigación Sanitaria, Santiago de Compostela, Spain; CIBER Fisiopatología de la Obesidad y Nutrición (CIBEROBN), Instituto de Salud Carlos III, Spain.
  • Dieguez C; Department of Physiology, CIMUS, University of Santiago de Compostela-Instituto de Investigación Sanitaria, Santiago de Compostela, Spain; CIBER Fisiopatología de la Obesidad y Nutrición (CIBEROBN), Instituto de Salud Carlos III, Spain.
  • Millet O; OWL Metabolomics, Technology Park of Bizkaia, Derio, Bizkaia, Spain; Liver Disease Lab, Center for Cooperative Research in Biosciences (CIC bioGUNE), Basque Research and Technology Alliance (BRTA), 48160 Derio, Bizkaia, Spain.
  • Mato JM; OWL Metabolomics, Technology Park of Bizkaia, Derio, Bizkaia, Spain; Liver Disease Lab, Center for Cooperative Research in Biosciences (CIC bioGUNE), Basque Research and Technology Alliance (BRTA), 48160 Derio, Bizkaia, Spain.
  • Cubero FJ; Department of Immunology, Ophthalmology & ENT, Complutense University School of Medicine, 28040 Madrid, Spain; Health Research Institute Gregorio Marañón (IiSGM), 28007 Madrid, Spain.
  • Varela-Rey M; Gene Regulatory Control in Disease, CIMUS, University of Santiago de Compostela, Santiago de Compostela, Spain.
  • Iruzubieta P; Gastroenterology and Hepatology Department, Marqués de Valdecilla University Hospital. Clinical and Translational Digestive Research Group, IDIVAL, Santander, Spain.
  • Crespo J; Gastroenterology and Hepatology Department, Marqués de Valdecilla University Hospital. Clinical and Translational Digestive Research Group, IDIVAL, Santander, Spain.
  • Martinez-Chantar ML; Liver Disease Lab, Center for Cooperative Research in Biosciences (CIC bioGUNE), Basque Research and Technology Alliance (BRTA), 48160 Derio, Bizkaia, Spain; CIBER Enfermedades Hepáticas y Digestivas (CIBERehd), Spain.
  • Schwabe RF; Department of Medicine, Columbia University, New York, NY, USA.
  • Nogueiras R; Department of Physiology, CIMUS, University of Santiago de Compostela-Instituto de Investigación Sanitaria, Santiago de Compostela, Spain; CIBER Fisiopatología de la Obesidad y Nutrición (CIBEROBN), Instituto de Salud Carlos III, Spain; Galician Agency of Innovation (GAIN), Xunta de Galicia, Santiag
J Hepatol ; 77(1): 15-28, 2022 07.
Article em En | MEDLINE | ID: mdl-35167910
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Carnitina O-Palmitoiltransferase / Células Estreladas do Fígado Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: J Hepatol Assunto da revista: GASTROENTEROLOGIA Ano de publicação: 2022 Tipo de documento: Article
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Carnitina O-Palmitoiltransferase / Células Estreladas do Fígado Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: J Hepatol Assunto da revista: GASTROENTEROLOGIA Ano de publicação: 2022 Tipo de documento: Article