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Re-engineered BCG overexpressing cyclic di-AMP augments trained immunity and exhibits improved efficacy against bladder cancer.
Singh, Alok Kumar; Praharaj, Monali; Lombardo, Kara A; Yoshida, Takahiro; Matoso, Andres; Baras, Alex S; Zhao, Liang; Srikrishna, Geetha; Huang, Joy; Prasad, Pankaj; Powell, Jonathan D; Kates, Max; McConkey, David; Pardoll, Drew M; Bishai, William R; Bivalacqua, Trinity J.
Afiliação
  • Singh AK; Johns Hopkins University, School of Medicine, Department of Medicine, Center for Tuberculosis Research, Baltimore, MD, USA.
  • Praharaj M; Johns Hopkins University, School of Medicine, Department of Medicine, Center for Tuberculosis Research, Baltimore, MD, USA.
  • Lombardo KA; The Bloomberg-Kimmel Institute for Cancer Immunotherapy at Johns Hopkins, Baltimore, MD, USA.
  • Yoshida T; Johns Hopkins University, School of Medicine, Department of Urology, Baltimore, MD, USA.
  • Matoso A; Department of Urology, Hyogo Prefectural Nishinomiya Hospital, Nishinomiya, 6620918, Japan.
  • Baras AS; Department of Pathology, The Johns Hopkins University, Baltimore, MD, USA.
  • Zhao L; Department of Pathology, The Johns Hopkins University, Baltimore, MD, USA.
  • Srikrishna G; The Bloomberg-Kimmel Institute for Cancer Immunotherapy at Johns Hopkins, Baltimore, MD, USA.
  • Huang J; Johns Hopkins University, School of Medicine, Department of Medicine, Center for Tuberculosis Research, Baltimore, MD, USA.
  • Prasad P; Johns Hopkins University, School of Medicine, Department of Medicine, Center for Tuberculosis Research, Baltimore, MD, USA.
  • Powell JD; Johns Hopkins University, School of Medicine, Department of Medicine, Center for Tuberculosis Research, Baltimore, MD, USA.
  • Kates M; The Bloomberg-Kimmel Institute for Cancer Immunotherapy at Johns Hopkins, Baltimore, MD, USA.
  • McConkey D; Johns Hopkins University, School of Medicine, Department of Urology, Baltimore, MD, USA.
  • Pardoll DM; Johns Hopkins University, School of Medicine, Department of Urology, Baltimore, MD, USA.
  • Bishai WR; The Bloomberg-Kimmel Institute for Cancer Immunotherapy at Johns Hopkins, Baltimore, MD, USA.
  • Bivalacqua TJ; Johns Hopkins University, School of Medicine, Department of Medicine, Center for Tuberculosis Research, Baltimore, MD, USA. wbishai@jhmi.edu.
Nat Commun ; 13(1): 878, 2022 02 15.
Article em En | MEDLINE | ID: mdl-35169141
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias da Bexiga Urinária / Vacina BCG / Fosfatos de Dinucleosídeos / Vacinas Anticâncer Limite: Animals / Humans Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias da Bexiga Urinária / Vacina BCG / Fosfatos de Dinucleosídeos / Vacinas Anticâncer Limite: Animals / Humans Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos