[Rosai-Dorfman intracranial histiocytosis: case report and literature review]. / Intrakranial'nyi gistiotsitoz RozaiDorfmana: sluchai iz praktiki i obzor literatury.
Zh Vopr Neirokhir Im N N Burdenko
; 86(1): 81-90, 2022.
Article
em Ru
| MEDLINE
| ID: mdl-35170280
ABSTRACT
Histiocytosis is a group of idiopathic diseases accompanied by metabolic disorders and accumulation of metabolic products in histiocytes. Isolated Rosai-Dorfman histiocytosis of central nervous system is observed in less than 5% of cases. The authors report treatment and follow-up of a patient with intracranial Rosai-Dorfman disease. There were symptoms of lesion of the left cerebellopontine angle and epileptic seizures. Preoperative MRI identified two tumors (posterior cranial fossa on the left and right-sided parasagittal neoplasm). The authors carried out total resection of supratentorial tumor, after 3 weeks - subtotal resection of tumor in posterior cranial fossa. No recurrence after total resection was observed. Irradiation of infratentorial tumor with a total focal dose of 50 Gy after 6 months resulted tumor shrinkage throughout 12 months. Radiotherapy with the same dose was repeated throughout subsequent 12-month follow-up period due to progression of this focus. This treatment had a positive effect, but new skull base foci occurred. The authors emphasize the effectiveness of total resection and lower efficiency of subtotal excision combined with radiotherapy.
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Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Histiocitose Sinusal
Tipo de estudo:
Diagnostic_studies
/
Prognostic_studies
Limite:
Humans
Idioma:
Ru
Revista:
Zh Vopr Neirokhir Im N N Burdenko
Ano de publicação:
2022
Tipo de documento:
Article
País de afiliação:
Federação Russa