Loss of chaperone-mediated autophagy is associated with low vertebral cancellous bone mass.

Akel, Nisreen; MacLeod, Ryan S; Berryhill, Stuart B; Laster, Dominique J; Dimori, Milena; Crawford, Julie A; Fu, Qiang; Onal, Melda

Akel, Nisreen; MacLeod, Ryan S; Berryhill, Stuart B; Laster, Dominique J; Dimori, Milena; Crawford, Julie A; Fu, Qiang; Onal, Melda.

Afiliação

Akel N; Department of Physiology and Cell Biology, University of Arkansas for Medical Sciences, Little Rock, AR, USA.
MacLeod RS; Center for Musculoskeletal Disease Research, University of Arkansas for Medical Sciences, Little Rock, AR, USA.
Berryhill SB; Division of Endocrinology, University of Arkansas for Medical Sciences, Little Rock, AR, USA.
Laster DJ; Bone Biomechanics, Histology and Imaging Core (BHIC), University of Arkansas for Medical Sciences, Little Rock, AR, USA.
Dimori M; Department of Physiology and Cell Biology, University of Arkansas for Medical Sciences, Little Rock, AR, USA.
Crawford JA; Department of Physiology and Cell Biology, University of Arkansas for Medical Sciences, Little Rock, AR, USA.
Fu Q; Bone Biomechanics, Histology and Imaging Core (BHIC), University of Arkansas for Medical Sciences, Little Rock, AR, USA.
Onal M; Center for Musculoskeletal Disease Research, University of Arkansas for Medical Sciences, Little Rock, AR, USA.

Sci Rep ; 12(1): 3134, 2022 02 24.

Article em En | MEDLINE | ID: mdl-35210514

Assuntos

Autofagia; Osso Esponjoso/metabolismo; Proteína 2 de Membrana Associada ao Lisossomo/genética; Chaperonas Moleculares/genética; Osteoclastos/metabolismo; Coluna Vertebral/metabolismo; Animais; Calcificação Fisiológica; Feminino; Proteína 2 de Membrana Associada ao Lisossomo/metabolismo; Masculino; Camundongos; Camundongos Knockout; Chaperonas Moleculares/metabolismo; Tamanho do Órgão

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Osteoclastos / Autofagia / Coluna Vertebral / Chaperonas Moleculares / Proteína 2 de Membrana Associada ao Lisossomo / Osso Esponjoso Tipo de estudo: Risk_factors_studies Limite: Animals Idioma: En Revista: Sci Rep Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos

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