Inhibiting collagen I production and tumor cell colonization in the lung <i>via</i> miR-29a-3p loading of exosome-/liposome-based nanovesicles.

Yan, Yan; Du, Cancan; Duan, Xixi; Yao, Xiaohan; Wan, Jiajia; Jiang, Ziming; Qin, Zhongyu; Li, Wenqing; Pan, Longze; Gu, Zhuoyu; Wang, Fazhan; Wang, Ming; Qin, Zhihai

Inhibiting collagen I production and tumor cell colonization in the lung via miR-29a-3p loading of exosome-/liposome-based nanovesicles.

Yan, Yan; Du, Cancan; Duan, Xixi; Yao, Xiaohan; Wan, Jiajia; Jiang, Ziming; Qin, Zhongyu; Li, Wenqing; Pan, Longze; Gu, Zhuoyu; Wang, Fazhan; Wang, Ming; Qin, Zhihai.

Afiliação

Yan Y; Medical Research Center, the First Affiliated Hospital of Zhengzhou University, Zhengzhou University, Zhengzhou 450052, China.
Du C; Academy of Medical Sciences, Zhengzhou University, Zhengzhou 450052, China.
Duan X; Medical Research Center, the First Affiliated Hospital of Zhengzhou University, Zhengzhou University, Zhengzhou 450052, China.
Yao X; Medical Research Center, the First Affiliated Hospital of Zhengzhou University, Zhengzhou University, Zhengzhou 450052, China.
Wan J; Medical Research Center, the First Affiliated Hospital of Zhengzhou University, Zhengzhou University, Zhengzhou 450052, China.
Jiang Z; Medical Research Center, the First Affiliated Hospital of Zhengzhou University, Zhengzhou University, Zhengzhou 450052, China.
Qin Z; Department of Urology, the First Affiliated Hospital of Zhengzhou University, Zhengzhou University, Zhengzhou 450052, China.
Li W; Changzhi Medical College, Changzhi 046000, China.
Pan L; Medical Research Center, the First Affiliated Hospital of Zhengzhou University, Zhengzhou University, Zhengzhou 450052, China.
Gu Z; Medical Research Center, the First Affiliated Hospital of Zhengzhou University, Zhengzhou University, Zhengzhou 450052, China.
Wang F; Medical Research Center, the First Affiliated Hospital of Zhengzhou University, Zhengzhou University, Zhengzhou 450052, China.
Wang M; Medical Research Center, the First Affiliated Hospital of Zhengzhou University, Zhengzhou University, Zhengzhou 450052, China.
Qin Z; Medical Research Center, the First Affiliated Hospital of Zhengzhou University, Zhengzhou University, Zhengzhou 450052, China.

Acta Pharm Sin B ; 12(2): 939-951, 2022 Feb.

Article em En | MEDLINE | ID: mdl-35256956

Palavras-chave

CPT-Exo, cisplatin elicited lung tumor exosomes; CTCs, circulating tumor cells; Collagen I; DOTAP, 1,2-dioleoyl-3-trimethylammonium propane; ECM, extra cellular matrix; EVs, extracellular vesicles; Exosomes; Fibroblasts; LLC, Lewis lung carcinoma; LLC-Exo, LLC-derived exosomes; Liposomal nanovesicle; Luc-LPX, Luc-lipoplex; Lung metastasis; NC inhibitor, negative control inhibitor; NC mimic, negative control mimic; PMN, pre-metastatic niche; Pre-metastatic niche; RNA-LPX, RNA-lipoplex; cDNA, complementary DNA; miR-29a-3p; miR-29a-3p-LPX, miR-29a-3p-lipoplex

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Acta Pharm Sin B Ano de publicação: 2022 Tipo de documento: Article País de afiliação: China

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