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Joint EURADOS WG9-WG11 rem-counter intercomparison in a Mevion S250i proton therapy facility with Hyperscan pulsed synchrocyclotron.
Zorloni, Gabriele; Bosmans, Geert; Brall, Thomas; Caresana, Marco; De Saint-Hubert, Marijke; Domingo, Carles; Ferrante, Christian; Ferrulli, Francesca; Kopec, Renata; Leidner, Johannes; Mares, Vladimir; Nabha, Racell; Olko, Pawel; Caballero-Pacheco, Miguel Ángel; Ruehm, Werner; Silari, Marco; Stolarczyk, Liliana; Swakon, Jan; Tisi, Marco; Trinkl, Sebastian; Van Hoey, Olivier; Vilches-Freixas, Gloria.
Afiliação
  • Zorloni G; CERN, Esplanade des Particules 1, Geneve, 1211, SWITZERLAND.
  • Bosmans G; Maastricht University Medical Centre+ Oncology Centre, P. Debyelaan 25, Maastricht, Limburg, 6229, NETHERLANDS.
  • Brall T; Helmotz Zentrum Munchen, Ingolstädter Landstr. 1, Neuherberg, 85764, GERMANY.
  • Caresana M; Energy, Politecnico di Milano, via Lambruschini 4, Milano, 20133, ITALY.
  • De Saint-Hubert M; Radiation protection Dosimetry and Calibration Expert Group, Belgian Nuclear Research Centre (SCK•CEN), Boeretang 200, Mol, 2400, BELGIUM.
  • Domingo C; Departament de Fisica, Universidad Autonoma de Barcelona, Plaça Cívica, Bellaterra, 08193 , SPAIN.
  • Ferrante C; Energy, Politecnico di Milano, via Lambruschini 4, Milano, 20133, ITALY.
  • Ferrulli F; CERN, Esplanade des Particules 1, Geneve, 1211, SWITZERLAND.
  • Kopec R; Institute of Nuclear Physics Polish Academy of Science, Walerego Eljasza Radzikowskiego 152, Krakow, 31-342, POLAND.
  • Leidner J; CERN, Esplanade des Particules 1, Geneve, 1211, SWITZERLAND.
  • Mares V; Helmholtz Zentrum Muenchen Deutsche Forschungszentrum fuer Gesundheit und Umwelt, D-85758 Neuherberg, Neuherberg, 85764 , GERMANY.
  • Nabha R; Radiation protection Dosimetry and Calibration Expert Group, Belgian Nuclear Research Centre (SCK•CEN), Boeretang 200, Mol, 2400, BELGIUM.
  • Olko P; PAN, Polish Academy of Sciences, ul Radzikowskiego 152, PL 31-342, Krakow, Kraków, 31-342, POLAND.
  • Caballero-Pacheco MÁ; Autonomous University of Barcelona, Placa Civica, Cerdanyola del Vallès, 08193 , SPAIN.
  • Ruehm W; Helmholtz Center Munich, Ingolstädter Landstr. 1, Neuherberg, 85764 , GERMANY.
  • Silari M; CERN, Esplanade des Particules 1, Geneve, 1211, SWITZERLAND.
  • Stolarczyk L; Dansk Center for Partikelterapi, Aarhus University Hospital Skejby, Palle Juul-Jensens Boulevard 25, Aarhus, 8200, DENMARK.
  • Swakon J; Institute of Nuclear Physics, Polish Academy of Sciences, Radzikowskiego 152, Krakow, 31-342, POLAND.
  • Tisi M; Helmholtz Center Munich German Research Center for Environmental Health, Ingolstädter Landstr. 1, Neuherberg, Bayern, 85764, GERMANY.
  • Trinkl S; Bundesamt fur Strahlenschutz Neuherberg, Ingolstädter Landstraße 1, Neuherberg, 85764, GERMANY.
  • Van Hoey O; Studiecentrum voor Kernenergie, Boeretang 200, Mol, 2400, BELGIUM.
  • Vilches-Freixas G; MAASTRO, Doctor Tanslaan 12, Maastricht, 6202 NA, NETHERLANDS.
Phys Med Biol ; 2022 Mar 08.
Article em En | MEDLINE | ID: mdl-35259730
ABSTRACT
Objective Proton therapy is gaining popularity because of the improved dose delivery over conventional radiation therapy. The secondary dose to healthy tissues is dominated by secondary neutrons. Commercial rem-counters are valuable instruments for the on-line assessment of neutron ambient dose equivalent (H*(10)). In general, however, a priori knowledge of the type of facility and of the radiation field is required for the proper choice of any survey meter. The novel Mevion S250i Hyperscan synchrocyclotron mounts the accelerator directly on the gantry. It provides a scanned 227 MeV proton beam, delivered in pulses with a pulse width of 10 µs at 750 Hz frequency, which is afterwards degraded in energy by a range shifter modulator system. This environment is particularly challenging for commercial rem-counters; therefore, we tested the reliability of some of the most widespread rem-counters to understand their limits in the Mevion S250i stray neutron field. Approach This work, promoted by the European Radiation Dosimetry Group (EURADOS), describes a rem-counter intercomparison at the Maastro Proton Therapy centre in the Netherlands, which houses the novel Mevion S250i Hyperscan system. Several rem-counters were employed in the intercomparison (LUPIN, LINUS, WENDI-II, LB6411, NM2B-458, NM2B-495Pb), which included simulation of a patient treatment protocol employing a water tank phantom. The outcomes of the experiment were compared with models and data from the literature. Main results We found that only the LUPIN allowed for a correct assessment of H*(10) within a 20% uncertainty. All other rem-counters underestimated the reference H*(10) by factors from 2 to more than 10, depending on the detector model and on the neutron dose per pulse. In pulsed fields, the neutron dose per pulse is a fundamental parameter, while the average neutron dose rate is a secondary quantity. An average 150-200 µSv/GyRBE neutron H*(10) at various positions around the phantom and at distances between 186 cm and 300 cm from it was measured per unit therapeutic dose delivered to the target. Significance Our results are partially in line with results obtained at similar Mevion facilities employing passive energy modulation. Comparisons with facilities employing active energy modulation confirmed that the neutron H*(10) can increase up to more than a factor of 10 when passive energy modulation is employed. The challenging environment of the Mevion stray neutron field requires the use of specific rem-counters sensitive to high-energy neutrons (up to a few hundred MeV) and specifically designed to withstand pulsed neutron fields.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Guideline / Prognostic_studies Idioma: En Revista: Phys Med Biol Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Suíça

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Guideline / Prognostic_studies Idioma: En Revista: Phys Med Biol Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Suíça