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Dosimetry of a novel focused monoenergetic beam for radiotherapy.
Moradi-Kurdestany, Jamshid; Bartkoski, Dirk A; Tailor, Ramesh; Mirkovic, Dragan; Harel, Ze'ev; Bar-David, Aharon; Kleckner, Michael; Borukhin, Shirly; Salehpour, Mohammad.
Afiliação
  • Moradi-Kurdestany J; Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, TX, United States of America.
  • Bartkoski DA; Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, TX, United States of America.
  • Tailor R; Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, TX, United States of America.
  • Mirkovic D; Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, TX, United States of America.
  • Harel Z; Convergent Radiotherapy and Radiosurgery, Tirat Carmel, Israel.
  • Bar-David A; Convergent Radiotherapy and Radiosurgery, Tirat Carmel, Israel.
  • Kleckner M; Convergent Radiotherapy and Radiosurgery, Tirat Carmel, Israel.
  • Borukhin S; Convergent Radiotherapy and Radiosurgery, Tirat Carmel, Israel.
  • Salehpour M; Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, TX, United States of America.
Phys Med Biol ; 67(7)2022 03 29.
Article em En | MEDLINE | ID: mdl-35272282
ABSTRACT
Objective. A novel treatment modality is currently being developed that produces converging monoenergetic x-rays. Conventional application of dosimetric calibration as presented in protocol TG61 is not applicable. Furthermore, the dosimetry of the focal point of the converging beam is on the order of a few millimeters, requiring a high-resolution dosimeter. Here we present a procedure to calibrate radiochromic film for narrow-beam monoenergetic 60 keV photons as well as absolute dosimetry of monoenergetic focused x-rays. A study of the focal spot dose rate after passing through a bone-equivalent material was also done to quantify the effects of heterogeneous materials.Approach.This was accomplished by configuring a polyenergetic beam of equivalent energy using a clinical orthovoltage machine. Calibrated films were then used to perform absolute dosimetry of the converging beam by measuring the beam profile at various depths in water. Main Results.A method for calibrating radiochromic film has been developed and detailed that allows absolute dosimetry of a monoenergetic photon beam. Absolute dosimetry of a focused, mono-energetic beam resulted in a focal spot dose rate of ∼30 cGy min-1at a depth of 5 cm in water.Significance.This work serves to establish a dosimetry protocol for mono-energetic beam absolute dosimetry as well as the use of such a method for measurement of a novel teletherapy modality.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Radiometria / Dosimetria Fotográfica Tipo de estudo: Guideline Idioma: En Revista: Phys Med Biol Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Radiometria / Dosimetria Fotográfica Tipo de estudo: Guideline Idioma: En Revista: Phys Med Biol Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos