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T cells expressing CD5/CD7 bispecific chimeric antigen receptors with fully human heavy-chain-only domains mitigate tumor antigen escape.
Dai, Zhenyu; Mu, Wei; Zhao, Ya; Cheng, Jiali; Lin, Haolong; Ouyang, Kedong; Jia, Xiangyin; Liu, Jianwei; Wei, Qiaoe; Wang, Meng; Liu, Chaohong; Tan, Taochao; Zhou, Jianfeng.
Afiliação
  • Dai Z; Department of Hematology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, 430030, China.
  • Mu W; Department of Hematology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, 430030, China.
  • Zhao Y; Nanjing IASO Biotherapeutics, Nanjing, Jiangsu, 210000, China.
  • Cheng J; Department of Hematology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, 430030, China.
  • Lin H; Department of Hematology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, 430030, China.
  • Ouyang K; Nanjing IASO Biotherapeutics, Nanjing, Jiangsu, 210000, China.
  • Jia X; Nanjing IASO Biotherapeutics, Nanjing, Jiangsu, 210000, China.
  • Liu J; Nanjing IASO Biotherapeutics, Nanjing, Jiangsu, 210000, China.
  • Wei Q; Nanjing IASO Biotherapeutics, Nanjing, Jiangsu, 210000, China.
  • Wang M; Nanjing IASO Biotherapeutics, Nanjing, Jiangsu, 210000, China.
  • Liu C; Department of Pathogen Biology, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, 430030, China.
  • Tan T; Nanjing IASO Biotherapeutics, Nanjing, Jiangsu, 210000, China. taochao.tan@iasobio.com.
  • Zhou J; Department of Hematology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, 430030, China. jfzhou@tjh.tjmu.edu.cn.
Signal Transduct Target Ther ; 7(1): 85, 2022 03 25.
Article em En | MEDLINE | ID: mdl-35332132
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Antígenos CD7 / Antígenos CD5 / Receptores de Antígenos Quiméricos / Neoplasias Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Signal Transduct Target Ther Ano de publicação: 2022 Tipo de documento: Article País de afiliação: China
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Antígenos CD7 / Antígenos CD5 / Receptores de Antígenos Quiméricos / Neoplasias Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Signal Transduct Target Ther Ano de publicação: 2022 Tipo de documento: Article País de afiliação: China