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IgM anti-ACE2 autoantibodies in severe COVID-19 activate complement and perturb vascular endothelial function.
Casciola-Rosen, Livia; Thiemann, David R; Andrade, Felipe; Trejo-Zambrano, Maria I; Leonard, Elissa K; Spangler, Jamie B; Skinner, Nicole E; Bailey, Justin; Yegnasubramanian, Srinivasan; Wang, Rulin; Vaghasia, Ajay M; Gupta, Anuj; Cox, Andrea L; Ray, Stuart C; Linville, Raleigh M; Guo, Zhaobin; Searson, Peter C; Machamer, Carolyn E; Desiderio, Stephen; Sauer, Lauren M; Laeyendecker, Oliver; Garibaldi, Brian T; Gao, Li; Damarla, Mahendra; Hassoun, Paul M; Hooper, Jody E; Mecoli, Christopher A; Christopher-Stine, Lisa; Gutierrez-Alamillo, Laura; Yang, Qingyuan; Hines, David; Clarke, William A; Rothman, Richard E; Pekosz, Andrew; Fenstermacher, Katherine Zj; Wang, Zitong; Zeger, Scott L; Rosen, Antony.
Afiliação
  • Casciola-Rosen L; Department of Medicine, Division of Rheumatology.
  • Thiemann DR; Department of Medicine, Division of Cardiology; and.
  • Andrade F; Department of Medicine, Division of Rheumatology.
  • Trejo-Zambrano MI; Department of Medicine, Division of Rheumatology.
  • Leonard EK; Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
  • Spangler JB; Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
  • Skinner NE; Department of Chemical and Biomolecular Engineering, Whiting School of Engineering, Johns Hopkins University, Baltimore, Maryland, USA.
  • Bailey J; Translational Tissue Engineering Center.
  • Yegnasubramanian S; Department of Medicine, Division of Infectious Diseases; and.
  • Wang R; Department of Medicine, Division of Infectious Diseases; and.
  • Vaghasia AM; Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
  • Gupta A; Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
  • Cox AL; Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
  • Ray SC; Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
  • Linville RM; Department of Medicine, Division of Infectious Diseases; and.
  • Guo Z; Department of Medicine, Division of Infectious Diseases; and.
  • Searson PC; Institute for NanoBioTechnology and.
  • Machamer CE; Department of Materials Science and Engineering, Whiting School of Engineering, Johns Hopkins University, Baltimore, Maryland, USA.
  • Desiderio S; Institute for NanoBioTechnology and.
  • Sauer LM; Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
  • Laeyendecker O; Institute for NanoBioTechnology and.
  • Garibaldi BT; Department of Materials Science and Engineering, Whiting School of Engineering, Johns Hopkins University, Baltimore, Maryland, USA.
  • Gao L; Department of Cell Biology and.
  • Damarla M; Department of Molecular Biology and Genetics, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
  • Hassoun PM; Adult Emergency Department, Johns Hopkins Hospital, Baltimore, Maryland, USA.
  • Hooper JE; Johns Hopkins Biocontainment Unit, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
  • Mecoli CA; Department of Medicine, Division of Infectious Diseases; and.
  • Christopher-Stine L; Division of Intramural Medicine, National Institute of Allergy and Infectious Diseases, NIH, Baltimore, Maryland, USA.
  • Gutierrez-Alamillo L; Johns Hopkins Biocontainment Unit, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
  • Yang Q; Department of Medicine, Division of Pulmonary and Critical Care Medicine.
  • Hines D; Department of Medicine, Division of Allergy and Clinical Immunology; and.
  • Clarke WA; Department of Medicine, Division of Pulmonary and Critical Care Medicine.
  • Rothman RE; Department of Medicine, Division of Pulmonary and Critical Care Medicine.
  • Pekosz A; Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
  • Fenstermacher KZ; Department of Medicine, Division of Rheumatology.
  • Wang Z; Department of Medicine, Division of Rheumatology.
  • Zeger SL; Department of Medicine, Division of Rheumatology.
  • Rosen A; Department of Medicine, Division of Rheumatology.
JCI Insight ; 7(9)2022 05 09.
Article em En | MEDLINE | ID: mdl-35349483
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Enzima de Conversão de Angiotensina 2 / COVID-19 Limite: Humans Idioma: En Revista: JCI Insight Ano de publicação: 2022 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Enzima de Conversão de Angiotensina 2 / COVID-19 Limite: Humans Idioma: En Revista: JCI Insight Ano de publicação: 2022 Tipo de documento: Article