Homozygous variants in the GDF1 gene related to recurrent right isomerism and complex CHD in two Indian families.
Cardiol Young
; 32(12): 2041-2043, 2022 Dec.
Article
em En
| MEDLINE
| ID: mdl-35351224
ABSTRACT
Disorders of laterality are often associated with complex CHD. There is considerable debate about the appropriate terminology to describe these conditions. As our understanding of the genetic basis of these disorders improves, it is likely that terminology will be dictated by the genetic aetiology. The genetic basis of laterality disorders in the Indian population has not been studied. We report two families with autosomal recessive inheritance of isomerism and homozygous variants in the GDF1 gene in affected family members.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Fator 1 de Diferenciação de Crescimento
/
Síndrome de Heterotaxia
Limite:
Humans
Idioma:
En
Revista:
Cardiol Young
Assunto da revista:
ANGIOLOGIA
/
CARDIOLOGIA
/
PEDIATRIA
Ano de publicação:
2022
Tipo de documento:
Article
País de afiliação:
Índia