HER2 testing in metastatic breast cancer - Is reflex ISH testing necessary on HER2 IHC-equivocal (2+) cases?

Liwski, Christopher R; Castonguay, Mathieu C; Barnes, Penny J; Rayson, Daniel; Bethune, Gillian C

Liwski, Christopher R; Castonguay, Mathieu C; Barnes, Penny J; Rayson, Daniel; Bethune, Gillian C.

Afiliação

Liwski CR; Department of Medicine, Dalhousie University, Halifax, NS, Canada.
Castonguay MC; Department of Pathology and Laboratory Medicine, Dalhousie University, Halifax, NS, Canada; Nova Scotia Health Authority, Halifax, NS, Canada.
Barnes PJ; Department of Pathology and Laboratory Medicine, Dalhousie University, Halifax, NS, Canada; Nova Scotia Health Authority, Halifax, NS, Canada.
Rayson D; Nova Scotia Health Authority, Halifax, NS, Canada; Division of Medical Oncology, Dalhousie University, Halifax, NS, Canada.
Bethune GC; Department of Pathology and Laboratory Medicine, Dalhousie University, Halifax, NS, Canada; Nova Scotia Health Authority, Halifax, NS, Canada. Electronic address: Gillian.Bethune@nshealth.ca.

Ann Diagn Pathol ; 59: 151953, 2022 Aug.

Article em En | MEDLINE | ID: mdl-35487077

Assuntos

Neoplasias da Mama; Biomarcadores Tumorais; Neoplasias da Mama/diagnóstico; Neoplasias da Mama/patologia; Feminino; Humanos; Imuno-Histoquímica; Receptor ErbB-2; Reflexo

Palavras-chave

Equivocal; HER2 immunohistochemistry; HER2 in situ hybridization; Reflex HER2 testing

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias da Mama Tipo de estudo: Diagnostic_studies / Prognostic_studies Limite: Female / Humans Idioma: En Revista: Ann Diagn Pathol Assunto da revista: PATOLOGIA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Canadá

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