Blood Purification Studies in the ICU: What Endpoints Should We Use?
Blood Purif
; 51(12): 990-996, 2022.
Article
em En
| MEDLINE
| ID: mdl-35490671
ABSTRACT
The potential for treatment of the critically ill using blood purification techniques has been discussed for several decades. However, since the first attempts at applying extracorporeal techniques to patients with sepsis were described, there has been considerable hesitancy towards the widespread adoption of such methods, given the lack of mortality benefit observed and indeed the paucity of randomized controlled studies. However, this is not unique so far as studies on the critically ill are concerned where there is a dearth of studies providing a positive finding to influence clinical practice. Consequently, as well as targeted patient selection, it is perhaps time to consider endpoints other than mortality in studies on the critically ill, particularly in blood purification studies where, to-date, such heterogeneous groups of patients have been studied.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Estado Terminal
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Sepse
Tipo de estudo:
Clinical_trials
Limite:
Humans
Idioma:
En
Revista:
Blood Purif
Ano de publicação:
2022
Tipo de documento:
Article
País de afiliação:
Reino Unido