Fully-Automatic 3D Intuitive Visualization of Age-Related Macular Degeneration Fluid Accumulations in OCT Cubes.
J Digit Imaging
; 35(5): 1271-1282, 2022 10.
Article
em En
| MEDLINE
| ID: mdl-35513586
ABSTRACT
Age-related macular degeneration is the leading cause of vision loss in developed countries, and wet-type AMD requires urgent treatment and rapid diagnosis because it causes rapid irreversible vision loss. Currently, AMD diagnosis is mainly carried out using images obtained by optical coherence tomography. This diagnostic process is performed by human clinicians, so human error may occur in some cases. Therefore, fully automatic methodologies are highly desirable adding a layer of robustness to the diagnosis. In this work, a novel computer-aided diagnosis and visualization methodology is proposed for the rapid identification and visualization of wet AMD. We adapted a convolutional neural network for segmentation of a similar domain of medical images to the problem of wet AMD segmentation, taking advantage of transfer learning, which allows us to work with and exploit a reduced number of samples. We generate a 3D intuitive visualization where the existence, position and severity of the fluid were represented in a clear and intuitive way to facilitate the analysis of the clinicians. The 3D visualization is robust and accurate, obtaining satisfactory 0.949 and 0.960 Dice coefficients in the different evaluated OCT cube configurations, allowing to quickly assess the presence and extension of the fluid associated to wet AMD.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Degeneração Macular
Tipo de estudo:
Diagnostic_studies
Limite:
Humans
Idioma:
En
Revista:
J Digit Imaging
Assunto da revista:
DIAGNOSTICO POR IMAGEM
/
INFORMATICA MEDICA
/
RADIOLOGIA
Ano de publicação:
2022
Tipo de documento:
Article
País de afiliação:
Espanha