Human activation-induced deaminase lacks strong replicative strand bias or preference for cytosines in hairpin loops.

Sakhtemani, Ramin; Perera, Madusha L W; Hübschmann, Daniel; Siebert, Reiner; Lawrence, Michael S; Bhagwat, Ashok S

Sakhtemani, Ramin; Perera, Madusha L W; Hübschmann, Daniel; Siebert, Reiner; Lawrence, Michael S; Bhagwat, Ashok S.

Afiliação

Sakhtemani R; Department of Chemistry, Wayne State University, Detroit, MI 48202, USA.
Perera MLW; Department of Pathology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
Hübschmann D; Broad Institute of Massachusetts Institute of Technology and Harvard University, Cambridge, MA, USA.
Siebert R; Department of Chemistry, Wayne State University, Detroit, MI 48202, USA.
Lawrence MS; Molecular Precision Oncology Program, National Center for Tumor Diseases, Heidelberg and German Cancer Research Center, Heidelberg, Germany.
Bhagwat AS; Heidelberg Institute for Stem cell Technology and Experimental Medicine, Heidelberg, Germany.

Nucleic Acids Res ; 50(9): 5145-5157, 2022 05 20.

Article em En | MEDLINE | ID: mdl-35524550

Assuntos

Citidina Desaminase/metabolismo; Citosina/metabolismo; DNA/química; Escherichia coli/genética; Escherichia coli/metabolismo; Humanos; Switching de Imunoglobulina; Hipermutação Somática de Imunoglobulina; Uracila/metabolismo

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Citidina Desaminase Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Nucleic Acids Res Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos

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