Genetic Profiling of Colorectal Carcinomas of Patients with Primary Sclerosing Cholangitis and Inflammatory Bowel Disease.

de Krijger, Manon; Carvalho, Beatriz; Rausch, Christian; Bolijn, Anne S; Delis-van Diemen, Pien M; Tijssen, Marianne; van Engeland, Manon; Mostafavi, Nahid; Bogie, Roel M M; Dekker, Evelien; Masclee, Ad A M; Verheij, Joanne; Meijer, Gerrit A; Ponsioen, Cyriel Y

de Krijger, Manon; Carvalho, Beatriz; Rausch, Christian; Bolijn, Anne S; Delis-van Diemen, Pien M; Tijssen, Marianne; van Engeland, Manon; Mostafavi, Nahid; Bogie, Roel M M; Dekker, Evelien; Masclee, Ad A M; Verheij, Joanne; Meijer, Gerrit A; Ponsioen, Cyriel Y.

Afiliação

de Krijger M; Department of Gastroenterology and Hepatology, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, the Netherlands.
Carvalho B; Tytgat Institute for Liver and Intestinal Research, Amsterdam Gastroenterology Endocrinology Metabolism, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, the Netherlands.
Rausch C; Department of Pathology, The Netherlands Cancer Institute, Amsterdam, the Netherlands.
Bolijn AS; Department of Pathology, The Netherlands Cancer Institute, Amsterdam, the Netherlands.
Delis-van Diemen PM; Department of Pathology, The Netherlands Cancer Institute, Amsterdam, the Netherlands.
Tijssen M; Department of Pathology, The Netherlands Cancer Institute, Amsterdam, the Netherlands.
van Engeland M; Department of Pathology, The Netherlands Cancer Institute, Amsterdam, the Netherlands.
Mostafavi N; Department of Pathology, GROW-School for Oncology and Developmental Biology, Maastricht University Medical Center, Maastricht, the Netherlands.
Bogie RMM; Biostatistics Unit of Department of Gastroenterology and Hepatology, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, the Netherlands.
Dekker E; Division of Gastroenterology and Hepatology, Department of Internal Medicine, GROW-School for Oncology and Developmental Biology, Maastricht University Medical Center, Maastricht, the Netherlands.
Masclee AAM; Department of Gastroenterology and Hepatology, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, the Netherlands.
Verheij J; Division of Gastroenterology and Hepatology, Department of Internal Medicine, NUTRIM School for Nutrition and Translational Research in Metabolism, Maastricht University Medical Center, Maastricht, the Netherlands.
Meijer GA; Department of Pathology, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, the Netherlands.
Ponsioen CY; Department of Pathology, The Netherlands Cancer Institute, Amsterdam, the Netherlands.

Inflamm Bowel Dis ; 28(9): 1309-1320, 2022 09 01.

Article em En | MEDLINE | ID: mdl-35554535

The excessive risk of colorectal carcinoma (CRC) in patients with both primary sclerosing cholangitis and inflammatory bowel disease (IBD) was not explained by an extensive screen of copy number aberrations, mutations, microsatellite instability, and CpG island methylator phenotype status when compared with patients with IBD-CRC and sporadic CRC.

Assuntos

Colangite Esclerosante; Neoplasias Colorretais; Doenças Inflamatórias Intestinais; Colangite Esclerosante/complicações; Colangite Esclerosante/genética; Colangite Esclerosante/cirurgia; Neoplasias Colorretais/complicações; Neoplasias Colorretais/genética; Perfil Genético; Humanos; Doenças Inflamatórias Intestinais/complicações; Doenças Inflamatórias Intestinais/genética; Instabilidade de Microssatélites

Palavras-chave

colorectal cancer; inflammatory bowel disease; primary sclerosing cholangitis

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Colangite Esclerosante / Neoplasias Colorretais / Doenças Inflamatórias Intestinais Limite: Humans Idioma: En Revista: Inflamm Bowel Dis Assunto da revista: GASTROENTEROLOGIA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Holanda

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google