Childhood poverty, immune cell aging, and African Americans' insulin resistance: A prospective study.
Child Dev
; 93(5): 1616-1624, 2022 09.
Article
em En
| MEDLINE
| ID: mdl-35596670
ABSTRACT
The present study investigated developmental pathways that can contribute to chronic disease among rural African Americans. With a sample of 342 African American youth (59% female) from the southeastern United States followed for nearly two decades (2001-2019), we examined the prospective association between family poverty during adolescence (ages 11-18) and insulin resistance (IR) in young adulthood (ages 25-29) as well as underlying biological and psychosocial mechanisms. Results indicated family poverty during adolescence forecast higher levels of IR in young adulthood, with accelerated immune cell aging at age 20 partially mediating this association. Serial mediational models confirmed the hypothesized pathway linking family poverty, perceived life chances, cellular aging, and IR. Findings provide empirical support for theorized developmental precursors of chronic disease.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Negro ou Afro-Americano
/
Resistência à Insulina
Tipo de estudo:
Observational_studies
/
Prognostic_studies
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Risk_factors_studies
Limite:
Adolescent
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Adult
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Child
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Female
/
Humans
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Male
Idioma:
En
Revista:
Child Dev
Ano de publicação:
2022
Tipo de documento:
Article
País de afiliação:
Estados Unidos